PharmGKB is a database of curated knowledge about the impact of genetic variation on drug response


Includes or is also known as: Pharmacogenomics Knowledge Base

PharmGKB is a resourcee that collects, curates, and disseminates information about the impact of human genetic variation on drug responses.

  • Provides clinically relevant information, including dosing guidelines, annotated drug labels, and potentially actionable gene-drug associations and geneotype-phenotype relationships.
  • Curators assign levels of evidence to variant-drug associations using well-defined criteria based on careful literature review.
  • Provides a source of high-quality information that can support personalized medicine-implementation projects.