AR 1979 SIF ON NOTES ON THE R. & D. POTACY CONFERENCE 2979 Chewton Glen ... 10th February Torquay ... 12tht 13th and 14th February Present: E. Rittershimum (10th February only) F. Seebofer R.M. Gibb D. A. Sanford C.S.P. de Siquetra, R.G. Nichous L.C. Mackman S.J. Grelm co co r*-@ CIA, BAT Co LTD MINNESOTA TOBACCO LITIGATION The following spec if le alms were accepted for biological. research: W To understand how our products relate to: (a) present and foreseeable medical/govermnent pressures (b) those of our competitors. (H) To meet the requirement for more information (e.g. on BATFLAKE, PRT, stern etc.,) to aid decisions related to future processes and products. r L (M) To meet the need for short-term tests, e.g. Ames, K?WM and sebaceous gland. 2. It was suggested that the use of pure nicotine in skin painting should be considered Instead of nicotine citrate . and that consideration also should be given to obtaining further information from an Inhalation experiment. 3. The MOST attitude to nicotine as a possible benefit of smoking was noted, so also was the fact that encapsulated nicotine ban been withdrawn trom, the U.S. market - as a marketing deci3tan. 4. It was agreed that we have probably done enough laboratory work on menthol. co BAT Co LTD - MINNESOTA TOBACCO LITIGATION 2 - It was agreed that the NMFI test would now be given to the Canadian Authorities. If published, attribution to B.A.T. is not required. 6 . It was suggested that a small group at GR&DC (or perhaps Dr. Felton alone) should draw together an existing information M. on attitudes to tar, nicotine, carbon monoxide, nitrosarnines around the world with respect to the imposition of further external it constraints. 7. The importance of the behavioural, programme at GP-&DC was I but some concern was expressed that it might be attempting to cover too much. Some quest-Eons to be answered are-. Why smokers quit or 'switch brands? What makes smokers stay with a new brand? What motivates smokers in an increasingly hostile A environment? It was suggested that the WOODROSE procedure, which has performed wall for many years, has serious 11mitattons with low delivery cigarettes 9. There was some disagreement with the view expressed at GR&DC that enough work has been don* on compensation. A revisw of all important published and internal work an compensation might be useful at this stage. co rN%..) BAT Co LTD MINNESOTA TOBACCO LITIGATION 3 10. The general feeling was that the Leaf research programmes are not sufficient. Mr. Wood will be requested to review the various programmes in the Group and to advise on possible further integration or expansion. Mr. Gibb agreed to provide data on carbon monoxide and leaf grades. 11. It was agreed that, if possible, there should be Increased effort at A GRSLDC at a basic level, aimed to understand better the factors contributing to flavour effects In smoke. 12. Research on selective filtration of components which are likely to feature In future league tables should be continued. Irritants (actual and perceived) are a particular source of concern. 91 However, as deliveries become much less than 10 mg. tar, the contribution of filtration decreases. 13. There was some confusion on the position of non-wrapped acetate filters - particularly regarding the information avaiLible to Canada following acquisition c.f the BEE machine. A report an the current IV statuxpf NWA products Including available Information on market reactions win be considered. 14. 7he potential importance of the Bridon or stmCLar filters was acknowledged. Hasty reactions should not be allowed to obscm-C the longer term issues. co cr% BAT Co LTD MINNESOTA TOBACCO LITIGATION 4 - The likely increase In pressure In this area from the anti-sm.oking z lobby was noted. In the absence of threshold figures (e.g. safe levels ?I for nttrosamines) any measured number could harm the Industry. Consideration should be given to the possibility of establishing thresholds. 'ID 71 r 9 It was agreed that on nitrosamines some sighting shots should be aimed S an both ambient air and sidestream smoke. if 16. There was some concern that the proposed second stage of the combust ion programme at GR&DC seemed to suggest a further 5 - 20 years' research before new concepts of cigarette design could be formulated and tested. It was explained that this was not 30 (several novel e designs had already been tested), the (essentially short term) view was that the combustion programme should be directed more to commercial application for low delivery products. 27. It was also thought that more emphasis should be placed on the role of paper in supporting combustion between puffs In low delivery cigarettes, and the effect of varying the strand width, the packing density, and the influence of expanded tobacco. la. Research on aerosol growth between inhalation and exhalation offers a way of reducing the retention of tar without at the Sarno time reducing nicotine retention; this offers great potential to the Industry and should be continued. The apparent duplication in the German aerosol programme was considered. This work, however, is directly related to optimizing filters, and therefore complementary, to the work at GR&30C. -Co CC) C= BAT Co LTD MINNESOTA TOBACCO LITIGATION 5 - Co 29. ID r. Seehofer stressed the need for pulling together all methods, instruments and results on carbon monoxide determination. 20. Some members felt that the programme at GR&DC on process investigation was too heavily influenced by what was described as in-house thinking. My own interpretation is that the criticism was that the work is too basic. For example It was said that the "problem" was thought to' be located In the analytical analysis of the process - with emphasis on the lack of control instrumentation generany- Or again it was Said that there is a lack of understanding within B.A.T. of blending, and also of the origin of de-blending In the maker. - On the other hand, more needs to be known about the influence of the maker an cigarette firmness and also on the resistance to air flow and again the drytng/coottrig'area was thought to be worthy of particular attention. IP it was agreed that -.@hen mornbers had read Dr. Kilburn"&. technological forecast an the primary processes they would gftv some further thought to this area and write to me about It. 21. Som* concern was expressed that R&D members W Associated Companies had not been made aware of the now STRATEGi I Programme- We agreed to circulate a description of the project In some detaU to RLD colleagues. 22. There was agaemnent an the continuing need for better contrvl tnutrurnentatton for both primary mid secondary processes. It was suggested that central MM should be updated on current levels of instrument technology around the B.A.T. Group and then formulate C=k OL new cx 4&*a- "@6 CX:) BAT Co LTD MINNESOTA TOBACCO LITIGATION 6 a new programme based on a total systems approach. 23. Dr. S equeira saw the need for a quantitative test for hot collapse - both of the rod and filter - even though It was agreed that an instrument could not generally reliably reflect smoker response. 24. It was agreed that there should be unrestricted pooling of instrument development and plans - with an adequate level of security. - 25. Expanded tobacco is seen as major opportunity for product development, Including the reduction of deliveries. The aim should be to incorporate high loading and retain acceptable product performance - both for Virginia and blended products. 26. The development of alternative means of expansion was; still regarded as an Important research objective. 27. The undertaking of the U.K. Tobacco Industry to Initiate an epidemiological study on tobacco substitutes has not been carried out because of lack of smokers to carry out a study. I agreed to circulate the Calaneso consumer research on Cytrel in the U.K. co BAT Co LTD MINNESOTA TOBACCO LITIGATION 7 - The objectives of the present project on Total Product Design as presented to the Conference, were seriously questioned as far as major Companies are concerned. Certainly the Total Product Design package ought not to represent much of an advance for Companies represented at the R&D Conference except perhaps Brasil. It was thought, however, that as far as the research Companies are concerned the aim should be to extend TPD so that it could be used to formulate new products that are ahead of the competition. Ort reflection I think there is still confusion between the TPD project and our research programme on cigarette design. 29. The plans to increase the effort of the FDL work, mainly for Associates were noted. It was felt, however, that the M.P.D.C. should be encouraged to make a stronger 'product development" thziust from the centre (though not to cause basic R&D effort to be deflected). It was hoped that communication to the main Associates of the principal findings from the M.P.D.C./P.D.G./PDL work would continue. INF 30 rnformatton Retrieval It was agreed to adopt the main recommendation of the SRI Report, Tk namely that the lead should be at GR&DC where a co-ordtdator/facultator would be appointed. He will first establish the needs of Southampton* Hamburg and Louisville and then either recommend the system to be adopted, or the action that should be taken to Identify a suitable system e.g. 9 further contract with SRI or direct approach to a -commerc'W systems manufacturer. B.A.T.,Hamburg and B & W will each nominate a person to work with the lead man at GR&DC co 4b rl.-) BAT Co LTD MINNESOTA TOBACCO LITIGATION 8 31. Patents I agreed to consider the procedure for communication of patent information, possibly even before patents are filed. 32. It was suggested that there is still insufficient awareness within B.A.T. of the research content and strategy of major competitors. IL There is evidence that some competitors are putting in greater effort than B.A.T. 33. Aluglas requires careful consideration in some cases in the light of recent Canadian experience of the influence of pores on the transmission of taint. 3 34.' AU members confirmed the value of exchange visits of laboratory staff . While this is best left for individual Companies to initiate ft is necessary- to keep Millbank Territorial teams informed- 35. Reports It was agreed: (a) AU reports should have titles on the Summary page. (b) R&D managers will be informed when R&D reports are requested by, or sent to another department in their Company. C= M.) BAT Co LTD MINNESOTA TOBACCO LITIGATION 36. The following distributions were requested To U.K. I - Dr. Green 3 - Dr. Blackman To B&W I - Dr. Hughes 2 - Dr. Sanford (separate mail) To Canada 3 - Mr. Wade To Germany 1 - Herr Rittershaus 1 - Dr. Seehofer (separate mail) To Australia I Mr. Nicholls To Brasil Dr. de Siqueira It was agreed that the pattern this year should be repeated but that the small policy meeting could well be held before the reporting meeting and held possibly in U.S.A. early 1980. March, 1979 co cc t--4 BAT Co LTD - MINNESOTATOBACCOLITIGATION