2
CTMC to fund Verner Knott. Knott has already discovered that the equipment
he had proposed is inadequate and has raised his quotation to $140,000
with an option for a further $30,000. Bob Wade would like some involvement
by GR WC .
I have discussed this matter with Martin Oldman, Ray Thornton and Alan
Heard. There is a feeling that a well-executed project of this type
would be a useful contribution to knowledge. However, there are risks:
1. Misrepresentation by anti-smoking lobbies during and after the
project, possibly leading to political pressures to stop the project
before it is finished.
2. Ethical problems of disclosure of intent. The data could be predictive
of situations other than predisposition towards smoking.
3. Poor design and execution of the project leading to conclusions that
are both technically unsound and damaging to the interests of the
tobacco industry.
Involvement of GR&DC will involve considerations of change to several
aspects of Verner Knott's project:
a) Addition of a psychological and neurophysiological examination at the
end of the five-year project and possibly at year three as well: CD
b) Use of more than four EEG channels;
NJ
BATCo document for Province of British Columbia 19 April 1999

3 -
c) Direct digital recording of data to minimise distortion and loss of
information;
d) External resources to process the data both as a safety net and as
a support.
Providing improvements can be made, I would encourage Imperial Tobacco to
support the proposals. Specifically, Bob Wade would like Ray Thornton to
discuss the EEG aspects with Verner Knott in July and me to discuss equip-
ment, experiment design and data analysis with him when I visit Montreal
and Louisville to talk about future products.
12 J-L
c.c. Mr. A.L. Heard
Dr. D.G. Felton
Dr. M. Oldman
Dr. R.E. Thornton
cm
__4
4:%.
__4
N.)
BATCo document for Province of British Columbia 19 April 1999