Note to the Tobacco Strategy Review TM= conwr.Uum of Midemigl9gical Studies: 1291 Rey' The Cnqperdium has been revised to take ac=mt of newly publ i chili papers in any scientific Area re3evant to the objective of the cmpendium, rMely to highlight scientific papers of sukztarce uiuch do rot ccnfo= to the simple causal explanation of the association between smoking and certain diseases. In addition three Areas have been the subject of intense scientific debate in the last twelve months and bave expanded sections in the Compendium. (a) Cenetic predisposition of disease. (b) The role of viruses as a probable causal agent in certain cancers. (c) Allegations that the classification of certain chemicals as human carcinogens, an the basis of ani-I tests, is unscunay '-sed. This Mixtes to "biological plausibility", one of the criteria for deciding that an association. is causal. R E Thornton 3rd May 1991 U'l t.P4 Ln BATCO document for Province of BritiSh COlUMbia 23 April 1999