TABLE T Relationship between mutagenicity and chemical composition of tobacco and smoke - The significance of correlation coefficients from regression lines and Spearm- an rank tests Comparison between Correlation coefficients from mutagenicity (ITL) Regression lines Spearman tests and r r s Smoke Nicotine - mg/cigt 0.06 -0.31 TPM mg/cigt -0.07 0.08 Tar mg/ci9t -0.00 -0.14 Tar/nicotine ratio -0.27 -0.69* Acetaldehyde ug/cigt 0.09 0.17 Total aldehydes - ug/cigt 0.18 0.31 Acrolein - ug/cigt -0.50 -0.26 Tobacco -0.11 Total alkaloids - % 0.19 Reducing sugars - % -0.40 -0.73* Total -nitrogen - % 0.86** 0.72* Protein nitrogen 0.86** 0.66* Significant at P<0.01 Significant at P4 0.001 co C:> co BATCo document for Province of British Columbia 15 April 1999