TABLE Y Relationship between mutagenicity and chemical composition of tobacco and smoke - The significance of correlation coefficients-from_regression lines and Spearman rank tests Comparison between Correlation coefficients from mutagenicity ( ITO Regression lines Spearman tests and r r s Smoke Nicotine - mg/cigt 0.06 -0.31 TPH mg/ci gt -0.07 0.08 Tar mg/cigt -0.00 -0.14 Tar/nicotine ratio -0.27 -0.69* Acetaldehyde - ug/cigt 0.09 0.17 Total aldehydes - ug/cigt 0.18 0.31 Acrol ei - ug/ci gt -0.50 -0.26 Tobacco Total alkaloids - % -- 0.19 -0.11 Reducing sugars - % -0.40 -0.73* Total nitrogen - % 0.86** 0.72* Protein'nitrogen - % 0.86** 0.66* Significant at p<0.01 **-Significant at P.,_, 0.001 C:) (-P4 CN M-) BATCo document for Province of British Columbia 15 April 1999