B.Ar/
BRITISH-AMERICAN TOBACCO COMPANY LTD
A mcmNerofthc 13 A Ind U, I Group
Registered Office:
PO Box 482 Wcsirnri5tcr Hou,c
7 ASillbank London SkX"P 31E
Telephone: 3r-2zz izz:
Telex: 273S-' SATTOB G
Facsimile No: 0 1 -2:2 36 49
Professor B N' Ames,
Department of Biochemistry,
University of California,
Berkeley,
California 94720,
USA.
Dear Professor Ames,
I am a scientific adviser to the B.A.T. Group of companies and have
been closely following your work, particularly since your remarkable paper
in "Science" in 1983. In particular I have been following your views on
the evidence that implicates oxidative damage in ageing processes
generally and in carcinogenesis in particular. The probable importance of
oxidative damage has also been stressed by other investigators with whom I
have recently been in contact, including Dr H Bartsch of the Intern3tiOnal
Agency for Research on Cancer in Lyon. and Dr Francis Roe, an independent
toxicologist in London.
The potential importance of this area as far as the B.A.T. Group of
companies is concerned is underlined by the fact that several of the
people whom we support are currenti,. invoking various aspects of oxidative
damage to ration3lise some of their experimental findings. Consequently,
we are keen to receive an overview of this area. The purpose c1-7 this
letter is to enquire as to whether there is any possibility that you would
be willing to address senior scientific staff of the B.A.T Industries
Group of comoanies possibly at the annual meeting on research topics
scheduled for the week of 18th September. 1989 in Vancouver. Canada, or on
some other occasion and venue which is mutually convenient. It is likely
that the following countries would be represented:- Australia, 3razil,
Canada, Germanv,CK, USA.
B.A.T Industries is a diversified multinational Company based in
London and your audience will represent the principal Companies within the
Group. Although the B.A.T. Group of companies has tobacco interests. its
interest and involvement in fundamental science is much broader than just
tobacco chemistrv and toxicology.
If you prepared to talk to us we would meet all your reasonable
expenses and first class air faces (for example, Sat) Francisco to
Vancouver and return) together with an appropriate hon a ;'i thin the
broad remit of the area we would like addressed, there voul be no
constraints whatsoever on content.
0N
@z
in Lon%km Nambcr Cablos: Vchicukir London SW: all-
Loll
BATCo document for Province of British Columbia 20 April 1999

Ve are very much hoping that vou would be able to accept our
invitation and if you would like to discuss matters with me directiv I
shall be in the US and Canada in Hav this year and could visit you around
16th or 17th May, or possibly 22nd Mav.
I look forward to hearing from you.
Yours sincerely,
Dr R E Thornton
n.o.o.c.c. Dr F J C Roe
Mr A L Heard
REr/LES
5th April 1989
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BATCo document for Province of Brifth Columbia 20 April 1999