1@. EDIt Lt6 s,*,t;l lk L 0(4-r Ttte= Stmtwv Review Tom In Novud= 1989 a Dw structizvet for = in the GrcW vas prcposed, tbe bmis of vb4ch was that Fundmental reseexch sbomId be I I on cm establisibmint (W in soufteptm) and tMt other Gr=V ND omitres should corcareawte on appued R&D. An axtlim PM prowmw fcr the nm cmitz vas presented to the MU with a prqmmed btdgft. sinm Ist April, uhm the d=Vm we= effeCtAd, ttWe have bow a mx*w of vastuzp wft R0 and Xwftstirg Wxwt=, an =tcome of -*dch is tbo. rw4sed prograum new pmpowd to the MW, in smany fc=. (A detailed research I - - g m has bw dixtr@ to the CIC = Directors fcr fimi vormal). In the Pm=Aum presented a year ago, ommukrable eqftsis was pla@ an ruplatory-ttivun projects (reqn-IdiM either to D=xmt cc articipsted pmum=us), and on inmative Cowepts. As a rustat of the varlaw mestirsp that bwe tww place this r4ar tbiS Gqllaz" bas significantly chwW. 7be need to have tkxmdxts Wxich are m4mricr to 0343stitim 0artioularly Phil4p 11*=iS) is tbG clear QMW priority, amd this iZ rAW reflected intheirri-ml, ptuldamental I ;Lvgrmmm. 7his wm:k will wdetpin the cmwi@ effort being dev&Ad to tbis by the am' led P4D Contras. 7he other sajor dwip is in the area of ProlIct Iremation: si" the t4a as first priority the wmk alive at gVeriority of idxtiiig xtylem; of pro&=1 the ;rimity on research for n4e*-- =ZINts has bom 4 __ in iqx=tM=. Pbully, XT pmvje=x aixed at different d9areLtm (c. f. ft=Li=) hm bem 1=Wly shelved. For corwarderae. the work arms cmmered by the prcpowd prupa=g are stom in fo= catagornies %bich relate to broad busums Cbjectives: 1. D=MSW cmvetitivity ____ S=ke gality 14=70mmult. 2. 1 maed compstitbity nwntive pro&imts. 3. ]MW9JM " axqWV to pawfam its buirmn =kw J=TVw9m91Y restrictive Anamt=y Xvn==. 4. 1 hmhlirq the to I F'm its busirgm uTdw 3:n practice, them are very few pMects that caft1b2te to Cnly cm of thesis tusiness objectives, bLTt Vam a simjle f-1A ificatim would be misleadiM, the poift is IIiad*. The prqxrAd pro;mm fdr the Rvidamwtal. Research Centm is r\J now *&Iwad with projects %mqxd m1ft- tbme faxr d;]e=vm: CD B.A.T INDUSTRIES P.L.C. - MINNESOTA DEPOSITORY Copy - PRODUCED PURSUANT To VILD, OF CONSENT JUDGMENT DATED 51"S IN STATE OF fthWESOTA, ET AL. V. PHJLIP__WRW@ ET AL., CASE No. CI-9"565 SMO)m 0=lity Effort Allocation 35% I. O)MMMIsory This area of research is concemned with the relationship of -I,- Chemistry to taste, -11 ard other argancieptic Xtir-A. There are two I I q abjectives: (i) to relate chmical and physical properties of smoke, (across the full delivery range) to smokung savations as a basis for the developmit of supwi= pruaicts. (ii) for low tar/nic: ratio prods:ts, to identify ard CM the existuq barriAers; to swd=y accq*ability. Projects agreed cmw iqmrt and imtotion, --fta a Irtals:te and the sensations of "bW and "mme4n-till-, they w:LU relate these Il , to buman Smakin; behavimw. In arda to )teep this w=* relevant, much of it wJ-U be undertaken an sup' ssisaW and supplied by cac C=Pwdm. A special analytical research team %bich was fam=ly set up to handle regulatory im , has now re-oriented to give 0 to the above projects as a first: priority unless an =gw* regulat=y issue arl 2. InflIMM of Cicaretbe Design on S=ft As a gowmal cbserviktion PULP YACtriS I "14ch P=Iwm cigareLtes of good pkvdml propertUs at IVAW pressure dxCP than W. ftax is =w beliswd be the tM!@ Sonia 9:11slity. is mater= to Mviortigate the tL relationship bW:wsw physical Wqmtiw of the rod ani =ddxq quality. Pessarch will Inc:3,xie the effect of particle dwsity, size amd sbape and other ; rx , Changes on flow rates and PCNN= drops. Since SA= and BW have gathered information In this general arm, this will be reviand be tto exwt 1 1- - is defined. Mft= b2aLtuatim Over Y It yams Soutbanptcn W has pz=W a research pmect, the purpose Of uhich be$ been. to fird treatments that r-41 the subse9oft fdwsaticn of xmw ccq=zm' of intamt to Ro7dators. As a result of the variow GroW diso i0w, this project bas now broadwad su:b that qVortunitisswinalso be saxytt, thrxLrp sbdl= treatments, to nwdmi the fwastion of cospoxxis which iqxwwe the subjeftive gality of -,ka. mix NJ PrMect area Um rqpmds to both S=ke Q=lity and rw711&t=Y objectives. C" C:) C) PRODUCED PURr ANT To I VILD. OF B.A.T INDUSTRIES P.L.C. - MINNESOTA DEposiToRY Copy AJ CONSENT JUDGMENT DATED 518198 IN STATE OF MINNESOTA, ET AL v. PMLIP AfORRA ET AL CASE No. Cl-94-8565 Eawles of projects to be piurmied include: (i) Generation of flavour precursore such as mino acids, ammia and mxjar by bio-dumicad processes. (ii) MW effect of reconstitution pm%xx---ves an smWm wality- (i:Li) 7he effect Of dumical and biodxmical prommses on the fb2zatlon of minor sublose compongntg (Omer r=ae) - (iv) 7b& use of activated =rbon or molecular siew natarials; to r6duce Mir= CORWItibIWItS Of make or arlhance mmke qmlity. Frahcts Effort LU20=M,-,_ As a general Winciple spew with ths CAC CoupaIdes, any wmck in this am will be Ained at dwujnJM Wildi bl k oc s and not M prototype Products. The wivin pmer't in this catagory rMains ptuiect Qmul= Vhic@ tw as its obj'-ttv* d , pro ucts givinV hJQh1Y Udified =Ww tME123 of Oosposition and delivery. 7bo nein thrust of the research PrOWame is to cmwt* low tar/nic ti = o pro*xts for %hich tbers. is both Xm*&JM and jsjZ;@@ w4port. Whilst a oammIer pmajr-t trW on ths fi;rst spin-off of this wcXk is currortly bairg wdwW= by SUCO i ., w th ennaw&jjxq X'sults, the furdamental research aJ=d at rvd=M the tar/nic. ratio furtbw Will include Use of cast&-shwt Materials cbmical treatments Of tobacco and micZO-4030apsulated f1ravour materials. In the == gw=Ll area of creatiM buildiM b] am of the isporbInt tmmw is the afficlot Use Of In dftkd M the re*tired 0111ratrIstea and sidestZaam d-l1VQrJA.. 3@n =.M Fmiucts then is an e=aw of in relation to switar reQuitmefft, and t1hus =ww Of crsstiM Mtn-11g= j _1S = A=== an beinq pUrsLud. Although aLl wcm* AimWI at prcdLxdiV a radical altarnetive PrOdUCt that does not -1 S A on coubustion (c.f. Prester) has bow abandoned, aw am 9warated an iftmosstin; now direction. bamd On elutim f o volati Ie. m m t w 'a] s ' l be t e= ' l * ( l f' r o ut im -l t z) t h B t m m s f or t o x t z e m o f vo l a til e 3= t or W s t b a t a r o S W x u er waigtod in mq t i de y p c l oo er regions.) This wm* has dxm that the relem of n' OUTIO, Mthol and SaVaml OUW n&VC=Wft to the , In, straw can be influenced by the natum of the bir%Urq naterial. M21S work w:LU conti nue, and be wd=zW, to include stuliss an the migration of cmqxurds within the d ro , ard at the specific re*Jest of the CZC OmpImies, will include =rbw1als; migratiM from P=twim Materi l i a s, s nce these represent a source of off-taste problem. r@j cr, -M. B.A.T INDUSTRIES P.I-C, - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To VILD. OF CONSENT JUDGMENT DATED 5/8/98 IN STATE OF UNNESOTA, ET AL. v. PHILIP MORRIS, ET AL CASE No. C1-944k%5 PAmlatory Lmm Effort calccation ... 29 1. Tunitim % Altkmgh at tus stage crdy USh bas reAdatium that rAcamtote, estabLL*Am an accepted ratbod for mmamwirIq cigarette ignitim potm*4al, u3is is cIpmaw to sprew to other 0aftries. CCRMM ham mt up a task 15 in utach ST has taimn a prircipal lead. Activities plarvmd fbr 1991 are: furtbw collaborative studies. mind at refiriim the existing test method ft" evalustiom to mmme ommixtency and Wdf=ity of ocatim. In additim to this wcm:k wbicb is largely cmxxwd=ated an mtbads of meamamawlt, tbere win Ultinately be a rmwd for =wmzumts that wable predictium to be node of ignitim ptmtW of cigmettes. Wmk in this arm win in 1991. 2. Search for RigLvAW Tbam has bem catsiderable renew of a= a= in the of Biolajical TastJM, and it is prqmsed that the followiM pollcy rww uml%Vim the ftb= research activities in this am- - BAT wi.11 mmitor tru in the amzgwm of rxw bioessrys and will demUp mpwtim in *kich my have relevanm to tdm YLVdacts. - DeVite the mxmrta@ ampociated with m=,ent in vitro and their aW34emh414 to comw t Imixu tAwts are lim-All om way - if test resUts differ significwtly fLcm c=rwit - g they irdiCate that sme r4mical changs bas o==red and further n I is reWired. - Such tests as are curruitly available (Amms, , oft.) WiU be used to .11 0 TMW additives, or sigrdficent v P, , I dmqW baiM explored in PAD to cbeck put=betim frcm the nor&L - However, cn the kimmis of rmm 1: m I, scdmntific and mdical mvidwce, tberm to be m justifIcatim for 2&IW1dM MOM of ze*3=Uq values meamm-ed by the onm3ntly ffmilAble biculays, ard this will not be an Objective Of CLmTeft bzdanwftl research. 3. Additives ard Materials Advice 7he Work aria providw a service to cparatuq OcapaniAlsby reviEdirg inf=mtim an I I I now aIiditives and NJ mterials and mkiM rdaticm rwprdim uWir C@ Cn B.A.T lmoumms P.Lc. - MINNESOTA DEposrrORY COPY - PRODUCED PURSUAW To I VILD. OF CONSENT JUDGMENT DATED 5/8W IN STATE OF MINNESOTA, ET AL. v. PHILIP MOMRS, ET AL. CAsE No. Cl-94-8565 accqytability. it aim naintains an awareness of charges = lepsiation and review conf=aity of additwm to specific guidelines. Xt vaintains a databa an additives C=ou#otxt the BAT Gmip. Proaktaw used far the assessim7t. of both nem and adsting zaterials will Continue to be developed in conjumt1cin with mc nwiromoftl Tabscoo EavircIowntal Tdxcoo Smoke =*.iruea to be a =Jor ism- in the njority of the Graw's ) I , with sowe rewilatory authorities mcirstim that QRXNUM to ES my be ha-611 to non and recosounding restriLtion an %two swo)dM my occur. TI)e I I toss in Scud=q7tw have bt%iltup a considerable datebm on levels of MS in il world environeents and have wh' 4 abed these remits eaL r %1,daly. FollcedM the MW HwtiM in Wv=bw 1989, the level of research an EX ws rs&xmd, but it is important that we niLintain I 1 1 in this am&. The 1991 program will contilwe to foct an providing furdmental in.15ocantion an the dw-4-1 and physical rature of Els, on personal wpowre detamairiwtiam thLuIgh nicatire wtabolites, and an subjective aspect of EM. 2. Tttal 9 Althaugh xe*xxd sidestzom produc:ts my 111136ating opportunities as an invistive product, the =wt 111-1y driv:M 2-ce for bftV&Virq much Wc&xgz Will be wwirmusatal . Research to daft bas Indicated that certain conlitructions of dgereitte lesid to low s1destran @'wdnn, but as yet we bave no ftAmental Of the =*Aniss underlying this phemannon. it that this is sturlied in the n9l ; g 1 , in - z I,,, that f=tbar qVacbmities con be. created. Additionally, own effort will be devoted to wolorat=y research g' fw lov sidestrean products in Mxich effectively the Cdg0r8tta 63M not b= bft puffs. 3. EU= MUMdW& An a result of the Mm3wting Directare' meating, a new project has bow initiated, the PrJzary aim of -*14eft is to r-k the mvUuwwft1 pmblens associated with -'aarette Ix . 7he = therefore will focus priwipally an the acidification of C811111 acetaft ?41 to Permit Varying I a of degradability disguardW. 7his will be done in close consultation with NW. 0ansukratian, will be given to the ratn2ALs VWarq up the ti;pUq paper the glue, plu; wrep and plasticizer, as wall as to the fibtw. r1i A chaddist of the ism raised for brausion In this bzdisiontal C:D research I ; by the Harbeting Directors' and TW meetings in ro Arjust. and SWtwixw respectively, is sham In Appendix 1. CrN B.A.T INDUSTRIES P.L.C. - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To I VILD. OF CONSENT JUDGMENT DATED 6/8M IN STATE OF HNNESOTA, ET AL, V. PHXIP MORRIS, ET AL, CASE No. Cl-94-8565 Budoet 12W wm3t 1 is based an a tatal afftrt of 58 xw-r-ye&rs 2n the Flurdmiental 11mmearch OKdxe and will cost 93.885 millicn. C=Pri=M With 11WI I=Wt WM Uft a=MXTt that the creatim of the nC twk affect In April smd the fully wnalised rate f= the nm Cwft* fer that year would ban bow C3.632 axllian with the Chc =mpmnies). on this kmalm the iIncremse -. irjf3jidtim is 7%. It has bow a practice ever years to divide the allocaticin of catrib*11- to the txdaawftl rummarch programm by the CW campimies ao==Iirq to the follming i - , Ig : HAM. 32%; BW 30%, MAZY 19*, 3= 19%. On tais basis, irdividual all=ati= mad bet: WW. C1.243M. B&N ri.1646M. SkTa CO.738m. ED.738m. Quite sepwimrtely, there is a budgetary regairmieft of i296,ooo for exr=ml cmitracts cn mmkirq and bealth (Sciwitific PA"Arch QmIP praject g I by Dr. M. Tbc=rbm cn behalf of the. MC caqvinism). fte caiioparable figure for LM is C344,000. TraditiormLUy, this is ftzW an equal shares basis by the four cm*rih*.Uq cmc empudes, and thm for 1991 caftibuticm mild be C74,000. :@ist:u@ @ft= the= tto budget of C3.985 SCiGiltifiC 1110mearch Qmup Projects. ; 9, sm m, and 0%, 000 for In term of allocation fammilm, TMM in admd to g either the bistard beems fcc I I two budgets or to cmaidar an altwittive Amdirq howis stich lay am sces of tbq tax PrdgAm aNINXdAted Vith the CUrlift smystem A Wcpml for a fundirq frOV021A L*drb Partly ratlectS bzmoyw Of the cmitributim cm;mv is illustrated in Appindix n. AUVW 21st 11mmember, 1W cl- B.A,T INDUSTRIES P.L.C. - MINNESOTA DEPOSITORY Copy - PRODUCED PURSUANT TO VII.D. OF CONSENT JUDGmENT DATED 5/8/98 IN STATE OF UNNESOT& ET AL., V. PHILIp AfORRIS, ET AL., CASE No. CI-94-8565 Action Cw& Lift from Mrketim Dirwtors- and TSPT WA%J= Uwe vere a number of actions raised at these two meetings Much wmv to be o=idered at the neating of the Research Directors in octaber 199o, for inclusion, if apptupriata, in the fundanalal research v ma m. 7he foLlowim chacklixt 14 the decisiors of that vawtinq. 1 Projects alned at mstandim the @ U buift ZIL text* devalwiM products imlm iz !@5 A= to It was cacluded that this pri=ity is wall covered in the C)MWMMS=Y W015t &XM- SigMifiCUlt Parts Of the VAtGrialS SCiMMOS and Special Analytioal work areas also U%ix subject. AU relevant informati=I In BP= and BfiW on the effects of physical properties on wokim qmlity, tmother with vian on what f=tber inftmatim is needed, will be sent to FW. 2. Cheffasensory n== to M&M bitterness and With the proviso that bitterness" should be seen in the tatal colytext of 'aftertaste" and that "harshness" and "irritmtim" are closely linked, UAs priority is cmwed in the MemosavIory work Area. 3. A$1g;JaW work to understarid mookerso Mix is now included in the avwasensory work programs. 4. Delvelooment of iumvvw I I I for WJUL&Ifitim Ws is not am as a project arm fcr nniamental Pasearct. Bw will deflnet the soope of and iqAament this project, after disonsim with othw CAC compnim. 5. Donloo cigarettes with reduced nimt1w n=9 7his priority is covered in the Mwavative Pxvducts arm. 6. 110MMUIle EU= A new pvoject bas been Inclizied in the zzdamontal resserch pza;rnm to purmia V3JA pricrity. MW wc& win be dom in cmultatimVool.laboratim with &x=. 7. Idnitim PotAntial Aspects of Uiis priority are being: pursued in bott IMC and WN. M3a two approaches should be om*aementary with no dvaication of effort. 8. To investi=ts tdbao= leaf W&JW for M1 auality at Various lzr.kw A omprehensive revuw of wdstiM informatim, zuch of Vaich is based an experiments conducted in ftnil, v:Lll be madis by April 1991 by ScIrAft C=. AIWW C) IM Wmzbw, 1990 C:) Go B.A.T INDUSTRIES P.L.C. - MINNESOTA DFp0SffORy Copy pRooucEo PURSUANT To VILD. OF CONSENT JUDGMENT DATED S/8/98 IN STArE OF ammEsom ET AL v. PH&JP MORRIS. ET AL., CASE No. Cl-94-8565 Alternative Fundim Flormula The currm-st percentage split of allocaticm by the cAc cccpmues is based on a prcposaLl fr= the R&D CD-crdanatcr in 1986 which uas wylifl by the MW to reflect size of ccq=V and its contmbutim to QuIp R&D and tAchnolcgy. 7bm lack of a mtbemtical fonula upon which c=Ttrjbt&_jcn can be explained has bem a socirce of ,, ; Currently NUM is m%1w pressure ftm tax autboritim to accomit f= its cmtributiom to owltralized RO and finds the abswce, of a f-111a to be a real wea)mm. I= bwm similm concerns. in View of pmd)Ll= a f-,'-% is pmcposed that identifies two alownts: 1. a fixed by all cortribatorm ref:Le&-irq 'club wegbershipt, i.a. the benefit of bmirxj the HC fac-ility. 2. a variable cost reflecting the extent to uhich an individual Caqwy will benefit ftm the researnh i.e. a turnmw related elownt. 7he sinpl-t way to ombine these alements is to m3ke haaf of the total cost I fi I and the remainder 'variable'. The forniula re=mwdad on this barmi is: Ci IR (0.5 x 0-5) ( =i N ) mbere Ci individual contributim (ft) N 1, r of cmitributors Ti mt turnmw of cattzibutor in prwA= ymw (ft) = total net Ummer of contribut-ions in previous yaw (ts) It I of all centraliad PAD (i.e. mc & Sra) (Es) In pmctice, to =at tax withocIty requirwmft, the 02tribUticne muld prd3mbly have to be recalculated at yaw and and =rramticm mede such that t=xww in the existing year is used. Tbe cceparism of ciantributions f= 1990 by cmrztries usirxi the existing -"-A and tbr- raw formilm is as follow: ndstirq Now Fpc SWIGS TtItal CDOO rooo E000 WOO Bh=b. 1.162 0.086 1.248 1.241 BSW 1.089 0.086 1.175 1.289 BAV7 0.690 0.086 0.776 0.704 0.690 0.066 0.776 0.738 3.631 1 0-344 3.975_ 3.972 If the forrallis were agreed, the ally ism to be C=idezW c:) r\.) each year am ttw of the Research Pzmgra=es (both CYN Lrtt@ and w&Arnal) . C) 01. C) B.A.T INDUSTRIES P.L.C. - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To VILD. OF CONSENT JUDGMENT DATED 5/8W IN STATE OF A*NNESOTA, ET AL V. PHXV MORRIS, ET AL. CASE No. Cl-94-8565