Our ref: MGDIJP 31st March 1988 Dr. P, Aulbach, Brown g Wiiliamson Tobacco Corporation, PO Box 35090, Louisville, Kentucky 40232, US A, Dear Paul, Further to out recent telephone conversation on the subject of Di·ethyicitrale, the results obtained diftered behueen "ftesh" filters and paged" filters. Using filters two days after manufacture, the following deliveries were obtained: Code % DEC PMWNF Nicotine TarlNicotine A 0 13.1 0.86 15.2 B 2 13.1 0,69 19.0 tall deliveries in mg cigl) These results inspired confidence and a series of products was manufactured~ Deliveries for manufactured products were as follows: Code ~ DEC % Vent PMWNF Nicotine Tarlnicotine 8384 0 0 13.6 0.89 15.3 8384 0 33 10.4 0,84 12,4 8385 1.75 31 10.5 0.83 12.7 8386 2.03 18 12.0 0.82 14.6 8387 1.88 0 13.4 0.82 16.3 It should be noted that products 8384 to 8387 were manufactured some six weeks after production of the filters and the initial determination of deliveries, From these results and your comments concerning the isomerisation of DEC, it may well be the a case that filters with DEC go "otf" and the effect seen in the initial experiments O reduces with tirne, C: I i I; P D F - !::!!:K! ~3 St I C.i: D Ill I would be interested to know of the results that you have obtained and details of the analytical techniques that you use for DEC, Regards, Yours sincerely, M,G. DUKE (Dr,) d Not on arioinal: cc: Dr, T, Hirji Mr, J,A, Luke Dr, C,R, Jenkins Clit; PDF -!:~:!.f3 StlC.i: 0111 " $~P -~. K "" ·~ ,r. I!bca ~iiti3o dgJJ !O )Jigc~ Clil;PDF - !::!!::!!::!:f3stlc.;:nlil ;~·o ·-~ ~~.· 1--···.· r~S, : .· an! d.~:· d~ L;.:f tr~~" r:·' ·:r·cr: r; ,ai, c: .. : -, i c;r 5·/. · . :· - rr~s ·· '·'~ ·' · " ;~·.·. ac :n r,~. "·:':' : ::IG :··'·;'· ~:~:i' Zs::· ·I ·· c; i4.L.I ·(·:I: 1. · ,,lo.g 7CI ac·mj g ; ~Ld S 111 b O.L~ ~ny bi~ O Cr: Crl O Cn Clit; PDF -!::!!::!!::!.f3 StlC.i: 0111 ~bPCF ~JS ~I ~;~ sn# 1·:3 =.3 31~G~ ar c;aEaa; $1 ~~A; ~~LB~ ai I ~) R~~E aP · E~~i if RBtS 89 ;r; al rt a~ GZQ g~; I~B~B;a~aiYaB ;r RPDCEI BESli BUi · XSnCSL G I F ET RI · ~m~Ei ~1F ~6i nl Le luTg3a~!t FL; 18Sn ~r 18 r~; E;1T ~L P85 EDI CLLr ~Plf3 tU~ 1BU RnOQ1Y885 I~P thi~~lO 1IR UY~ R1 8;~ Si ZEb Ela% 1B~r Yt~i ~~=3L 6:is~: lli PFUI!I iLE~B~ ajr~SI E36~ :~4E! Du~nnulhulnoiPnula .E pUM~nMOI~U~nUlnPUPI ClibPDF - v~~fastio.soni 3 0 ·i U ~)o~~LBII ~rl*Q ~,>l·.~r~~h~ h p0ll UU ·~YI OOQCO~ · :1 ' · ' ·b ' ' '' W 3 rl ·: lcJ 3 r ''" FI I· C Qh 50101~LOLN OaR*h :,.gj:, L'I 1 m,n UU·3P QQ90t '::'' ·.I)···' 0 ·f f I\ rl ·e ~ ··:3 5:111011~ 11 I i: u ~IZ C I-- "1: =4 rl st Ilh r~*nS0DL~ no,o, ,I 0 DQn OU·ll'l ~h9m~ ·IDI I · · wt 3 II II e ·~ 3: I·:J i~l::·C:;Ill~ CL(1 r* r "~ :1 "I 3u Il ?I 0~ iC LI r +n c,O~~iQ~s M~h"O h*'15 ::.lllc31r\ h ~ pi m311 UU'3L1 OhQml~l · ·C··''' ~~lrl '* !· 'r3 ,, ·,ZPIP· pi a ~S ;z o "~ iC :C rl 0'1 U~ t IIQ re OrC~Oah r hhPI~I I!,0,: :·'·D~`\O(D e 5 01 DOD~1 ou·~n ,~sm~ ·:1 ·· ,.o···· ,,,, .,,,~,, :, ~.~onw n e P + FI U~ ZW rl ~ u: 3 05 uz Z PhO*~iLUCO~ n0)*0 I·:5t: ~:lbr:~mP) Il) ~ (DQII ou'~n o~P·omn ·u·· ··~···· o z m Il e ·* n ·ri F"·*SrlC O W r r "~ 00 II 02 ;i~ ~go~~8~iic~ nr~g*~O r,~~~o c~:og'·J~u II L r Ppri OU'3'3 D,IlhOe '·'' ..3·..· D r 0 Il ·* n,C3 C:l'e:·IIP n W c 0 " n Up 30 pt OiCL r r O .cr-·n~ W C*··"·l~~'*~ nnn~r, I 9t4653149 3454.0 93iJ rJQJJdu Q *vvuv **~r *r**u·~* X PhOTCiinB~ pRp·12 nrh4 rsnn:D·I i: E o,II90e ·:~ ·~ ··"·''' O t JC Ihn UU '3W O Il ii tI Il ~~ M 'C3 ·I 1' 10110~ i~ 3 ii '0 r II II a ~ LI &L n ~ t Iw r 5 p Qi~ P Lri '" II· U pr 003 e~06~ YI 3 r .'I ~2~~; r3*re PI 3 I ji C' o 333 3333 L]L;Ou~ O S ~ 1 31 sio 333; i :L II fttr 0 L1 ~TLtT 13=OE:l 3 iii 31 trfP u r rttOO ilNYN rfETE) D ~ i;i 3 I 'w W c ~Ww ~~ 3 3 ~'~:1:: 51 LI W ul o .oo~un~ ·~·~~-~· rl XLfC~L~t r O u WI WtW~r~~ ; .* ~1 L1 t: I ~:~U·rUi~" Je~~w *t~c·:l .; I ·U.I~ tWYI 4 I1JU~*IL W U Q ,,,.,~u~~;ris·e~3i ;t;; 1Lie 3 Or*t"ewlIW 00I0u 'c-l r·~Etl~ C ~I rUcS~rLL3 cYrYiL 2,13 i-ZJ~3C ;I L (1111111)1)111 ,111lN C: I i I; PDF -!::!!::!!::!.f3 StlC.i: 0111 eS,: it:I ft~ 1Elv 1?i7 Project ~E~~la f ~Er' ~lca~ure 1~ enelo~ln~ 1 are:rct Etop:rai fct Ef6 Ef Cf.efsvlCffTi:C II ? !fJt.er'aGGlt!v~, if?ce !lvl ay euctin, DlaSS; t0llt3tt eF~ Fea~S. Esc. cc: nr, f, ~~rjl r,r, J,I, [u~e Cr, 9,4, Crcll~e 0r, C,6, kat~ns Clit; PbF -!::!!::!!::!.f3 StlC.i: 0111