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                   &hJ Ill~and Export) limited
                   RI~E3RCH~ OEYtlOlulY: CLNTRI

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          ~lr. A, P.. C~usins           Dr, Y, r,, Ouke


                          15;:L
          115Clnn                       2Ctr! April, 1988


                      PRAIECf DECAME


         r,:~jli:n of ?i-e!hvlci!r3!3 to cellulese 3cer":e fil:ers has been studied to
         j3till·mlae the effect on nie:tine deJiVPfjts '?!ffiYC to filters Without the

         sldi:i·:4, This nrxe sumnarises the fir,din~s to oate.
         ~~nn fresh filrsl·s were ~it2ched to pr,! j~~!Cp*O rods a decrease in
         nicotine deliveries was ?ooa,rent:

          :FE;r~
                 1?.1
          he 13,1 13,?


         i!c~we~llr, these nEslrs ,e,, not O~talne~f fr?m samples manufactured on
         mJchine some six wcske after the filters were made, as illustrated by
         the fclibwine:


          C!ia /~ ?E!: l~ven~lrrw~·1Fl Nico:ins I Tarlwic3iine

          e:en    o i          13,8           15.3
          ~e3c?   n       3?   10,d   O,el    12,6
          D1OL  I~:r I    3) i        O,ES I
          8395  2.0?      19   120    0,g?    1c,6
          B?e:  l,t!t! i  O    I?,o   Ola?    18,3


         ~rilade to PS1 specification

         There is a small difference in nicotine delivery and Tar/nic ratio
         betw~~r E?~a !~r vs!lt) and 8387 but it is not as large as the initial
         study suooested, Comparison of 8384 and 3385 (31x ventl indicates that
         there is no effect on deliveries with DEC added to the filter, However,
         it is :n:Enr,tin3 to nrre that the nicc!ine Cslivetv for 8384 to 838'1 is
         simi;r.l., hu! fhPrP if a CiifePenCe in PMWHI: deliveries as the ventilation

         chan3es from O to 33X.
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         I1:is:~ssicn wi:a Cr~ P~ Aulbach (ebn!.:e suggested t~s:~;h the
         C~: an~ filters csuld go "off" due to is:7leriSation, HP i~3S found that
         I?lf nE: will iscmeri9P to give only 5~t 2EC over a PPr;?lJ Cf time,
         This has obvious product consequences :1 terms of storage time and
         sne!~ life, oarriculari!: for the Middle fa: market,

         ~I~ SP!\6?rY testing has been carried ou: to date since the anaiyticl
         rPS.JltS have not justified the tests. C]plrance for use of Dr.': filters in
         ~c~~ei :·5:s was obtained on 31st March :088 so in any further work,
         S;nS:r~ tests could be carried out,

         CONCLVSrONS

         The ~64r,t of PEC as a filter additive to reduce the nic:!ine delivery
         14'!t!v4 to tar waS Smaller than eXCn~:;:~ ThiS was due to the possible
         i~?~~ris3tian of OEC both during transt?rt to RaD and after filter
         rr;pn~:e~:ure~ Without further work It is not possiblete establish the
         tiapsczia for this process,

         In ;ic~ of the above comments and rer,!!s, it is unlikelj: that DE,:
         h:~ld he effective for reducing nicotine relative to tar for the Middle
         E!~: market, Further data on the iocerisation is being obtained from


            a!""


         c,c, Dr. T, HiTji
           Mr, J, A, luke
           Or, C, R, Jenkins


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