__

                                            3~
       SECRET

       Note to II C~ Brown, Esq~

                         Greendot

         Whirst I am impressed at the speed at which Greendot is
       progressing, I have serious concerns for the validity of pursuing
       the current route based on incorporation of a nicotine salt into
       tobacco sheet,

         As you well know, arguments rage over whether or not the
       Reynolds' product will be classified as a cigarette and one of the
       important issues is whether or not nicotine occurs "naturally"
       within the tobacco land is not added by some fortification
       means)~ I have asked Sharon Bcyse to clarify the validity of
       incorporating nicotine or its derivatives by the methods you are
       pursuing for those countries where the product is likely to be of
       interest.

         Until we have a really clear signal that we can proceed by the
       current route, I feel it is imperative:::at we keep a very open
       mind in selecting technical options to achieve the Greendot
       objective~

         I am enclosing a rough draft of a note which Bob Johnson
       produced on his work with tobacco substitutes which was an
       important focus of his activities 18 months or so ago, You will
       see some close similarities to the ar!Droach you ale developing
       with Greendot currently, It should be stressed, however, that in
       the ease of 8&W's work, the initiative was not to create a
       commercial product but to develop means of understanding the
       sensory characteristics of dmake more prcroundlyl In the current
       approach to Airbus I saw no reference to nicotine foxtiEifation.
       Indeed, in order to increase nicotine delivery from tobacco, BhW
       are looking at inclusion of DA? or, more interestingly, at the use
       of Y1, the high nicotine flue cured varie:yl

          r would appreciate your comments on ::?is very important issue,

                         G1~(1V·
                         R~t. Heard


       clc~ Or, R~ Binns


       ALRIDET
       22Ad July 1988


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