INTRODUCTIO14 THE PROFUCT IN THE EARLY 198ns 2 5 I-Ap 1,176 ACK - FILE...- In the past twenty years there have been sevetal forecasts of the demise of the cigarette. The majority reflect little more than a popular, reas oned- argument forecasting the reaction of our consumers to the continuous dual pressures of anti-smoking publicity and increasing taxation. Forecasts based upon the emergence of a rival to the cigarette are rare, but the use of marijuana and nicotine-containing chewing-gum, as discussed later, have been suggested. 2. In general, the smoker has shown marked resilience in resisting these pressures. So much so, that it raises the danger of complacency within the cigarette industry. Equally, of course, there is a danger of over-reaction to the forecasts of gloom and doom. 3. This document considers the main threats to the smoking habit, the probable constraints an the type of product in the future, and draws attention to the undoubted opportunities which exist in the development of future products. THREATS TO THE SMOKING HABIT 4. Probably the greatest threat lies not in further evidence of a direct link between smoking and disease, but the increasing tendency to portray smoking as a socially undesirable habit. Philip Morris have pointed out that upper-class smokers are more successful at quitting than are lower-class smokers (1) . In the U.K. , the trend (2) is towards smoking behaviour becoming a working-class habit (Table 1). Table I Percentages of Smokers of Manufactured Ciqarettes bV Sex and Social Class Men Women Regis,trar General's Social Class 1 1961 1973 1961 1973 1 Professional,etc., occupations 53 39 46 26 11 Intermediate occupations 59 42 44 42 III Skilled occupations 59 so 47 47 IV Partly-skilled occupations 60 56 49 46 V Unskilled occupations 62 63 411 47 V! Unoccupied 40 34 24 26 ALL SOCIAL CLASSES 59 50 43 44 BATCo document for Province of BritiSh Columbia 5 November 1999 - 2 - It will not be easy to combat this threat; Good Public Relations activitfes are likely to be more effective than bcience-based research. Particularly in the U.S.A. and Germany, part of the attack lies in the attention being focussed on the side-stream smoke, and exhortations are made to the non-smoker to demand his right to breathe clean air. The Tobacco Research Council currently has a small working party considering the social implications of a sustained and successful httempt to portray smoking as socially undesirable. In the discussions, attention was drawn to the potential erosion of the social fabric which could arise from the polarisation of the population into smokers and non-smokers, with each group showing increasing intolerance and demanding their "rights". Taking a long-term view, there is a danger in the current trend of lower'and lower cigarette d *eliveries - i.e. the smoker will be weaned away from the habit. Sweden has a 25-year plan to produce a generation of non-smokers. In countries where tar and nicotine league-tables exist, a feasible scenario is government pressure on the advertising support for high-delivery brands, the introduction of legislation to limit the delivery of brands to be followed by a step-wise reduction in the limit. The reduction in tar deliveries is not of critical concern and, providing the pressure on the market is sufficient to cause an "across-brands" tar reduction, opportunities are opened'up in the market for a low-tar-with-taste cigarette. Despite evidence from Germany that smokers will both accept and stay with a low- nicotine cigarette, other markets could well have a different reaction. Nicotine is an important aspect of "satisfaction", and if the nicotine delivery is reduced below a threshold "satis- faction" level, then.surely smokers will question more readily why they are indulging in an expensive habit. It is advocated that every opportunity is taken to separate tar and nicotine in the minds of consumers and legislators, and that we should be aware of the long-term dangers of following the crowd into ultra-low nicotine deliveries. 6. Before outlining future constraints and opportunities for cigarette design, it remains to consider potential rivals. Included in'the rivals are cigarettes in which nicotine has been replaced by an alternative pharmacological agent. (a) gjq~!Kg_and Pip2 -There is no indication of a major upsurge in the pppularity of cigars and pipes. (b) Chewing-t9~~!222,-EBMfl-~'Dq-DicOt ine- containing_St2,L41ng:_q9Ln These are potential rivals if cigarette smoking becomes socially undesirable. Sweets; or confectioneries containing nicotine carry the danger of over-dosage - nicotine is an acute poison. The interesting thought remains, however, that if a modern, product development team was charged with the job of designing an oral method of administering a five-minute dose of nicotine, it is unlikely that they wou Id come up with a saliva-producing cliewing product which also carried the problem of disposal of the soggy residue! BATCo document for Province of BritiSh Columbia 5 November `1999 - 3 (c) Modified nicotine It is theoretically possible to modify the chemical structure of nicotine and produce a compound which retains the positive attributes of nicotine but has a minimum of any adverse side-effects. Opinions vary on the chances of success. It is sometimes argued that a low probability is attached to the possibility of a compound producing a recognisable and attractive physiological response but also having a virtual absence of side-effects. When considering the mass sale of such a material it is clear that an immense amount of biological testing would be a necessary pre-requisite. On the other hand, if the net is widened to include compounds which are not based on nicotine, & technological forecast published in 1971 (3) predicted that the period 1971-1981 would see the intro- duction of new, safe drugs for mood control, crime reduction and personality control. A second technological forecast in 1974 (4) suggested that drugs will be used in the late 1990s to ameliorate specific conditions and control specific unwanted behaviour. (d) _51t2rn~~tive_plant_products "Narcotic Plants" (5) 'lists some eighty species of plants containing hallucinogens, stimulants, inebriants and hypnotics. Nearly ten years ago,.a French paper (6) discussed numerous plants which might replace tobacco. The only material which has received a lot oi attention is marijuana, and the controversy on whether or not to legalise soft drugs has been frequently aired. In the last two years the public debate appears to have receded - one cynical explanation offered is that the habit has now extended to include "the establishment" or upper-classes. In the illicit use of marijuana, relatively large doses of the active principal are involved. If the use of such drugs was legalised, one avenue for exDloitation would be the augmen- tation of cigarettes with near sub-liminal levels of the drug. It is argued that a distinction exists between drugs acting on levels of brain activity (such as nicotine and some other stimulants) and drugs acting on the state of consciousnesa (such ~s marijuana, LSD and other hallucinogens). In this sense, nicotine and marijuana are not direct comnetitors. (e) Biofeedback .As inferred in the above paragraph, smoking (largely via nicotine) may assist people to control the level of activity in the brain to a desired level. Other means of such control represent, therefore, a rival to the cigarette. There is an increasing amount of evidence (7, 8) that subjects can control their levels of brain. activity, without recourse to drugs, if they are' given information on the level of brain activity (biofeedback). Currently, the equipment required is over-simple or cumbersome, but last year the editorial column of the gritish Medical Journal (9) drew attention to the potential clinical use of biofeedback. \~o Such techniques might be used by anti-smoking clinics. 1-0 BATCo document for Province of British Columbia 6 November 1999 4 We are aware from some unpublished work at St. Bartholomew's Hospital, London, of indications that only occasional practice with a modern biofeedback machine is required to enable a subject to exert significant control .over his level of brain activity. Summer training courses may not be socially unacceptable - the Delphi forecast already mentioned (4) suggested "Development of brain stimulation: Do-it-yourself pleasure centres.become a technical possibility, 1990-2020.". The date might have been closer had they been aware of the work at Bart's. The class of smoker most susceptible would be members of the nicotine-dependent.majority who have a high concern for health. 7. Summarising the rivals, however, it is unlikely that a major, serious contender to the cigarette will be established in the period 1976-1985. CONSTRAIkS 8. There are moves to extend league-tables to other smoke constituents. For several years various suggestions have been made that vapour-phase league tables are "imminent". Hydrogen cyanide.and alAehydes were frequently mentioned - largely because these constituents are effectively removed by carbon filters and, presumably, the possibility existed for a manufacturer or a carbon-supplier to seek commercial advantage. More recently, attention has been drawn to the nitric oxide content of smoke, whilst today the most realistic nominee is carbon monoxide. It is relatively easy to measure the level of carbon monoxide in blood and thereby monitor a direct effect of smoking on the human body. Many authors, e.g. Wald (10), link carbon monoxide with the 'development of heart disease - which is, of course, a major killer in westernised countries. Whilst the attack is not to be welcomed, it has the advantage of diluting the assertion that nicotine provides the link between smoking and heart disease. 9 Whilst it is unlikely that we shall see, in the next ten years, league-tables directly based upon biological testing, severe constraints are likely if the "Hunter Committee" approach is extended to other countries. Most attention has been focussed upon tobacco substitutes. In the next decade however, more serious constraints could arise from the need to use '.approved!' flavours and additives. If we are precluded from markettesting new flavours until they have "cleared" even the first stages of bioassay, then the search for new flavours becomes a very expensive prograrLne. it follows that B-A.T. should accelerate any market testing in new markets of distinctive flavours (i.e. flavours of the clove type), or perhaps materials of the ginseng type, before the possibility is foreclosed. 10. The shortage of agricultural land, as forecast for example by the Club of Rome, is unlikely to affect tobacco production seriously by 1985. Leaf Department will have forecasts available of the potential shortage of any particular grades or type of BATCo document for Province of British Columbia 5 November 1999 -.5 - leaf. A point to note is that there appears to-be a trend towards low-nicotine varietles. As is discussed later, B-A.T. will need a supply of high-nicotine tobacco, and steps may be necessary to reverse this trend. The increase in labour costs, the trend towards mechanical harvesting, and new forms of curing will lead to a decline in the number of grades.we currently enjoy. Tax harmonisation and allied moves can already affect the type of product offered, e.g. U.K. Changes in disposable income, vitally important in some markets, are difficult to forecast for periods beyond the immediate future, and other people within B-A.T. can obviously offer more sensible comment. Similarly, no attempt is made to forecast political trends which could have a major effect on B-A.T.'s ability to operate in some markets. Short-term shortages of humectants or plasticisers are always a possibility, although by 1980 the large fluctuations in prices experienced during the mid-70s oil crisis will have been accommodated. Cost advantages might see the dominance of acetate filters challenged by the use of other materials such as polypropylene - in one sense a constraint but, with adequate planning, an opportunity. OPPORTUNITIES 12. The design of cigarettes will become more systematised as progress is made in defining, in technical terms, the cigarette we want to produce, and in our ability to make it. The extension of league-tables to new smoke constituents Presents many oppor- tunities, since it will focus attention on the levels in smoke. A current example is the increasing use of porous papers and ventilation to control carbon monoxide. It is possible that smokers will polarise into "low-nicotine" and "high-nicotine" groups, and it is interesting to note a,recent call (11) for a low tar -low carbon monoxide- high nicotine cigarette. The need to control the level of other vapour phase materials will lead to th~ use of more complex filters,and adequate filter-making capacity will be required to take advantage of the opportunities. 13. At the present time, mouse skin-painting provides the main basis for much of the biological testing of condensate. Whilst filter and cigarette design greatly control the quantity of particulate matter from a cigarette, the specific activity is mainly influenced by the nature of the "tobacco" which is burnt. The next ten years, therefore, will see continued attempts to develop new smoking materials, and their incorporation at increasing levels in the cigarette. It does not follow, however, that man- made materials will erode tobacco usage. Indeed, a likely pattern is, because of experience from tobacco-waste utilisation, tobacco- based sheet materials will be favoured in some markets, and these will be followed by tobacco-based materials incorporating non- combustible inorganic fillers. Other markets will favour the use of inert diluents or the incorporation of man-made materials of demonstrably low biological activity. Whilst, at present, it is too early to predict which.type of new smoking material will BATCO document for Province of BritiSh Columbia 5 November 1999 - 6 - dominate, a common feature is that the tobacco portion of the blend will need to supply the necessary amount of nicotine and tobacco flavour to-the smoke. 14. Looking further down the road, the possibility exists that, as inhalation tests are developed and accepted, then filters might offer a selective means of controlling smoke toxicity. Well before that date, however, opportunities exist for filter and cigarette designs which offer the image of "health re-assurance!. 15. The control of both the quality and quantity of side-stream smoke remains an important research objective - i.e. an opportunity exists for the generation of a "product-plus" for our cigarettes. In passing, it is worth noting that in this area the patented ARIEL type of product (a "cigarette" which delivers an aerosol of nicotine and flavour with near-zero "tar") is in difficulties with regard to the quantity of side-stream smoke produced. 16. Whilst the pressures against the smoking habit will continue to grow, undue pessimism would be misplaced.. Many of the con- straints offer at the same time marketing opportunities. The trend in product design over the next ten years will be towards cigarettes with porous or ventilated wrappers, incorporating increasing amounts of sheet materials (both tobacco- and non- tobacco-based) , and carrying more efficient or selective filters. In other words, dramatic changes from the trend of the past few years are not indicated. C=) C__ C-1 . 1.0 BATCo document for Province of British Columbia 5 November 1999 7 REFERENCES 1. Ryan, P.J. in "Smoking Behaviour: Motives and Incentives". (W.L. Dunn, Ed.). V.H. Winston & Sons, Washington,. 1973. 2. Todd, G.F. "Changes in Smoking Patterns in t~e U.K.". T.R.C. Occasional Paper 1, 1975. 3. Parker, E.F. "Business Economist", 1971, 18. 4. Smith, M. "New Scientist", 1974, 90. 5. Emboden, W..."Narcotic Plants"; Studio Vista, London, 1972. 6. Cuenot, A. "Les Succ6dan4s du Tabac". Journal d'Agriculture Tropicale, 1967, XIV, 191. 7. Karlins, M. and Andrews, L.M. "Biofeedback". Garnstone Press, London, 1973. 8. Brown, B.B. "New Mind, New Body". Hodder & Stoughton, London, 1974.' 9. Editorial, British Medical Journal, 1974, 427. 10. Wald, N.J. "The Lancet", 1976, 136. 11. Leader in "The Times", January 19,76. BATCO document for Province of British Columbia 5 November 1999 APPENDIX In the main section of this note, a fairly broad brush has been used and the general nature of the conclusions reached may be regarded as inadequate. Indeed, it is difficult to avoid a feeling of disappointment that clear and specific changes in our product have not been identified. To be more precise, detailed considera- tion has to be given to individual markets and our marketing skills brought to bear to take advantage of the opportunities. With regard to the technical advances that will have been made by 1985, it is probable that the following features will be available: (a) A new generation of cigarette papers with a very high porosity - these will be made available largely to control the delivery.of carbon monoxide. (b) Filters with a higher particulate efficiency but acceptable draw resistance- these will be developed to meet the pressure from tar league tables. A trend towaras long*er cigarettes will allow an in:--rease in filter length (30mm will be common) which in turn will allow greater use of embossed or recessed ends, cross-flow and ventilated filter designs. (c) Filters made from cheaper raw materials than cellulose acetate. (d) The desire to provide "health reassurance" coupled with the need to control the vapour phase of cigarette smoke will lead to an increase in the use of granular absorbents in filters, e.g. modified carbons, ion-exchange resins, meerschaum, sepiolite and perhaps silica gel. (e) Sufficient non-tobacco sheet materials will be available for incorporation at a level of 25-35% in brands which have captured 10% of sophisticated markets. Since the use of tobacco-based sheet materials will also have increased, the pressure will have led to advances in flavour technology. The recent claims made for the brand Merit are a pointer in this direction. In several markets, figures are available for the tar and nicotine deliveries from cigarettes during the past ten years, and trend analysis allows some indication of the future. For example, it was recently pointed out in The Lancet (12) that, in the U.K., the average tar delivery is decreasing: July 1972 21 mg June 1975 19 mg The "banding" in league-tables forces manufacturers to achieve delivery figures within a series of steps. By 1985, therefore, the popular cigarettes will probably be in the "low-middle" band - i.e. 11-16 mg. The longer cigarettes in the U.K. market, which folloes from the change in taxation, will retard a general move into the "lo,.*'L- band - i.e. 10mg or less. The rebruary issues of The Lancet illustrate the semi-public debate taking place in the U.K. Russell (13) has suggested that it "seems to be urgent to publish CO yields along with tar and nicotine". 011 \-O 1-0 CO BATCo document for Province of British Columbia 5 November 1999 2 Recently (14), of course, a CO league table has appeared in Switzerland. Peto (15), at the D.H.S.S. Cancer Epidemiology and and Clinical Trials Unit, has forecast the effect of a series of price increases on cigarette consumption in the U.K. Based upon his earlier analysis (16) of price changes since 1951, he suggests a 10% price increase reduces consumption by 5%: he has put forward the figures in Table 2 to illustrate the effect of a .10% price. increase each year. Table 2 Projected Effect of Price Increase on Consumption Price of 20 Cigarettes Actual Price (E.) Consumption Year W (Assuming 10% (% of 1975) (1975 Values) Inflation) 1975 0-50 0-50 100 1980 0-80 1-30 77 1985 1,30 3-36 60 Trend analysis has, of course, anticipates sudden large changes.. U.S.A., a lot of publicity is being manufacturers in their attempts tb of the market. Even in individual ten-year forecasts are difficult to REFERENCES 12. The Lancet, 13. Russell, 14. Stiftung 15. Peto, J. 16. Peto, J. serious pitfalls and in no way For example, at present in the given to the battle between the ::apture the low delivery segment markets, therefore, precise make. 14 th February, 1976. M.A.H. The Lancet, 7th February, 1976. fUr Konsumentenschutz. February 1976. The Lancet, 7th February, 1976. Br. J. prev. soc. Med. 1974, 28, 241.