IG FgUF ?rr 5 F, and flerelpmot TO 'DR. S.J. GREEN FROM D.J. WOOD MILLBANK V REF DJW/JP/46D DATE 18th May, 1977 REPORT NO. RD.1494 RESTRICTED "ANALYSIS OF N'-NITROSONORNICOTINE IN TOBACCO AND OTHER SMOKING MATERIALS" This report describes a radiotracer method for the analysis of N'-nitrosonornicotine (NNN) in tobacco, and gives results for the amounts found in a restricted range of tobaccos and other smoking materials. According to our measurements the major portion of NNN which is found in smoke is due to direct transfer from the tobacco. This is somewhat different from Hoffmann's findings, who reported rather more than half the NNN in smoke as being formed during smoking. If our results present a truer picture the implication is that efforts to reduce the amount of NNN in smoke, other than by filtration, should concentrate on the tobacco rather than on the combustion process. There is evidence that some reduction can be achieved by reconstituting tobacco into sheet. I would suggest that copies of this report should go to Mr. Sheehy, Mr. Bowra and Mr. Walmisley. Encs. -2 c cc~ BATCO document for Province of BritiSh Columbia 5 November 1999