RESTRICTED 30 th Hay 1977 File Copy No.1 TO: MR. P.SHEEHY ~ZE2 MR. R.ST.C.WALMI Y No.3 MR. C.BOWRA No. 4 The appended Rep,-)rt (RD.149-1 Rer;trictcrl) May seew., at first sight, to bc- nimply a tcchnizal analytical report, of interest to laboraturins jnly. However it oresents 'ata on th--~ levcls f-)und in t~ibac---:) '.~f a material, 141-nitron.:)n)rnicotine, t,hi~..:h 1:-, a kn~)t;n carcinogen, also found in t::~baszco 5;"w.Ae and i~ -;iPnti:)n,ad in the forthcoming R.C.P. Rep~-rt. Prc-.-ViDunly' -,-.u n'...; t': e! carcinon-c-nic agents have been found to bc~? largely during the burning of the t--;ba~:c:). In thi.- in.;;tan-:- thc -riaj-)r fraction of this natticular material in -noke t-,an.-:f(-r.-- from the tobacco. The implication uf this is that eff-~,-t-.- to reduce this -iaterial in smoke, ~Aher than by filti.ati-,n, should be concentrated on the tcbacc-.~, rath(,r- than --n th,7, combustion procesr. There is eviden~~e thr)t F.W11P can be achieved by reconstituting tobac,---1, int-) -he-t 'in,1 further work is underway to explore the influence of b~,th nitr.ooen fertilization and curing an the formati-Dn c;,f this substance. Enc: D.G.FELT014 c.c. Mr.D.J.WoDd cc BATCO document for Province of BritiSh ColUrnbia 5 November 1999