L It L Cr L' r c: Stxztwv RevigM ZM-nmeLIM 30th November, 1"Q "C" Pbesearch Prourmme In Hcvmber 1989 a row struct=e for Ro in the GrmV was Imed, the basic of %ftich was that Fwztmm=l PAsearch 6c@UIA be - "' I an eMblishmM (nC in Soldweptm) and that other Group M I -dead acIzzritnte cn a;W J ad M. An outline M pro;rm= fcr the raw ow=e was prusermad to the TS= with a proposed bxkjet. sirce lat April, St= the chwqm Were , there brm bem a . z of msetirqs with R&D and tuq Dixw--irs, an o==m of which is the revised pro;nmm raw pr%4=9md to the TOM, In s=niry fam. (A detailed research ;M-oc--'@ t= I distributed to the CKC R&D Directors for firml appeal). Mm the prcTrjc= preswited a year ago, ccraiderable aWbasis was placed an regulatcwr-dr-ven pMects (ruspmAirg either to cmmum or =icipeted pm-am), wd an irmovative ; I I. As a rewlt of the v=- meetings that ham taken P3 mom this year this mvha-i- has siWaticwItly dmx_md. 7h& nod to ban ; I the priority cn niche bum real -in =p=t-- Firmlly, -W pLvjecft &immd at rudioully dif-1--it &-;aret:r- (r-.f. pnotigr) heye here largely shelved. Far ccnveniw=e the wmk areas cmmwed by the I I 11 g are shmn in fcur catmc:mries %oh' r!h relate to wroad busirmn d7je&-tvas: 1- Mmc:rmused onImpatitivity thr-xp -Q-1- qUaUty ixpx-uomlt_ 2. M=umd Q=petitivity throlub umm=iVe - I 3. EmInlin; the CmpwW to , M its bndrom urdw incz-airgly rm--ictive Fm7slatcry preamnm. 4. Emblim the OmpW to I M its bulsiIIIIIIIIII; urder increasing Erwixcmmvml omwerm. In Y=ctim, there are very few pv)je= that cmil:ribita to =Uy cm of theme hair- objectives, but where a mirale classificatim .=,'A be misleadiM, the paim is mmds. C> US fcr the Fbndamwcd Research Cm=m is row cutlizad with Praje= grcupmd urzbw these fo= cbJec:tives: C> B.A.T INDUSTRIES P.I-C. - MINNESOTA DEPOSITORY Copy - PRODUCED PURSUANT To VII.D. OF CONSENT JuDGmENT DATED S/11518 IN ALATE OF MINNESOTA. ET AL. V. PHILP MORRIS, ET AL- CASE No. Cl-944Lss5 sm*e cualirl Twr--@@ Ef f am allozatim .... 35% 1. chollosemmy Pjase-11ch mis --w of ressuch is =warned with the relsti-shiP of ---ka chemistry to tme, -11 and atkuw erganoleptic senset1cm. M=s am two broad d;jec-Uves: (J) to relate d-i-1 and p1rjsi=l prWartier. of =01- (aem-cas the full delivery range) to mmkin; sensations as a bade far the dAved g I of =*en= pro&-ts. (Li) for low tar/nic ratio wahh--s' to identify and overccm the exxstvq barn-mrs to sensory . . kility. P=dects agived cover imme- and ix---taticn, --ka aftertaste wd the senwdens of "bo:!y" ard "midifull", they will relate these phanotmem-A to hmn mokLrxj bdwvja=. in ordier to kup this work relevant, n3ch of it will be urderta)wn an -les selected and mapplied by CZC cccr -'ani as. A sPeci Al analytical research "" Uuzh was fc=wrly set UP to hargils regulatory iftft@' has r=w ' re-criented to give m;port to the above proj , as a first pz=wity unless an urge= rw3ulatary issue arism. 2. Trifluenme of Cloarette Dwi= on SmWm Cuality As a gworal doservation Failip Morris process tdmc= 1'hie-h I I Cigarettes of good pkmical properties at tlt@L,a kL- I.,.r pr. ftw than ST. main in now bal to be Macau m manka >4 tba c mcwx 2& tborefcwa zelatimship babiew physical of the to== rad and =mkirq qmUty. ammexch will kabzm the effec-- of M=ru dwaity, Size and -%qm and than promess chmps cn flow and gs drWs' Since WI= and B&W has gm*azud Infcamstim in this general art-, this will be ravismad before the cm= programm is dafinad. 3. --- - - over I . years Soadmpton PAD hm P==-11 a Pronct, the p=p=o of stdr-11i bas been to find too= tbwt re&= the oftacpa= facmetim of comoras of lrgmzmt to FAVAat=s. As a result of the Various Q=:p e14--i-0, this project'has; now broaftod Imch ttlat opportmitims will &Iso be max**, th=xjh similar . , to modmiss the fammatim of cativatz"Ift -A"c% iqzwa the WAbjectrve, quaLity Of simake. axis project imrse, tb2z I ; I to both Q-'Am Quality wd PATAlstUry objectives. C, '@4 B.A.T ImousTmEs P.LC, - MINNESOTA DEPOSITORY COPY PRODUCED PURSUANT To VILD. OF CONSENT JUDGMENT DATED steM IN STATE or MINNEsOTA, ET AL V. PHILIP Alogms. ET AL- CASE No. Ci-94-esss E-les of projects to be pi=uad include- (i) Cienstration of f1mlax p=acLxr=rs sLIch as amino g@iglk, a=wnia and px;ar by bio-chmical procesmes. (ii) ne effect of reociristitz-tim processes on C-AR, gality- (iii) The affect of chemical and bio-ch-J-1 processes on the form2tion of mu= smoke c=pumms, (other r-) . (iv) 7he use of activated ca=bm or mol-11-or sivis laterials to rat= min= ccrutitwits of -a or wft= saicks qmlity. IM03=n Bmuu Effort allocation .... 2D% As a gurnmal principle a=uai with the chc o=panies, any work in this area will be aimed at desuguM buildirg blocks and not prcltotyk- px-,-=. 7b& vAin project in this Category remins pmwt greandott Much hu. as its objective products giving biqftay --Aifi-4 M-k. in of cmpositun and delivery. Mw mm thrLsst of the zisualch ; g , is to create, low tar/nic. ratio I for i time is both Mar5crting and RWlatory uIpport WAlst a ccnsu=cr proluct trial an the first spin-off of this want in oxczently bLiW undarta)m by BA=., with enoomragirg reoults, the fumImmintal regauch &'mm at zut=irq the tar/nia. ratio, father will ircluk use of cute-sheat usteriAls, treatments of tobacco aid nicr*-arcupsulated flavo= Materials. Mm the --a gwaml arm of Crulatim buildim h, oil=, GM of the important thenes in the efficient =a of tobe= In dfim@ the required mainstream and sidestzma daliuscies. In ; I I three is an excess of taboono in %station to ru*dreasift, and tb= mews of creatirg Mtra-li= 3rj= === a- being p=mmd. Altba3gh all wock almed at pro*=zq a radical alternative yxadh= that does not I I; I an tam= ocutioutian (r-f- Vremisr) has been abunicned, awr am I 9 I I an laturestIM new dixection based an *lutim of volatile WAINcials. Me tom refus to the S to a 90111 r of volatile nituicials tha we WAM7xintly dwosit-4 in owler zw*=.) 2his wctk has shcun that tba release of nicatim, mmitbal and several other flavo=ants to the smoke XtZIMIIIL can be infl:uerved by the n==a of the birdim ustutal. MIJS work will =can=, Wid be wdxffxw, toinclude 0--44- cm the migration of owy=d- within the tcboc= rod, mend at the qag:jf4@ V a of the CXC C=VW40Q, will materials migmtirig from packagirIg moscials, since these a I smxrce of off-taste prCtilms. OF. B.A.T INDUSTRIES P.LC. MINNESOTA DEPOSITORY COPY PRODUCED PURSUANT To VILD. OF CONSENT JUDGMENT DATED 518/N IN S@T,,E , MNNESOTA, ET AL v. PIRLIP Mong-s ET AL- CASE No. C1-94.M5 ammgatmy Tss-'m E-1for. Allomticn ... 28t 1. PAd=ed Tgni-tion E=CaUal Although at this stop only USA has rugulatuzIs that namssitate establishing an Accimpted -thod for =m==2r%j WWWtte igatim potei@' this is expected to greed to other camcries. CMWA have set up a tnk f=m in this-, BAT Ims taken a primi;ml lad. Activities plarrAd for 1991 am: - further- collaborative =idims mism at refinirg the Wdst--q test mthod - fabric evalunticrs to armwe ocIsistercy and Wlifo:=ity of costim. in additim to this wm* which is larWly =zxr=mted an din= of measuramem, them will ultimtaly be a i@for In== =W=x=mWzts that mkble to be -- of iWdticn potm=al of ciWattes. Work in this arm Wm c=mw= in 1991. 2. fim= for Ripassays Mmm has ban conLiderable review of our aim in the arm of Biological Testim, ard it is ; r - j I that the falloAm PmLicy row underpus the == ressax-ch activities in this area- - MT vill mmitor tzuxk in the smargum of row humsmys Wid WLU develop mpartim in thaw which my have relumcm to tobacco pmuk=ts. - Dempits the uzIourtmAnLy amocisted with in vitro tests wd "-i- to oceplax mixtures, thmest taste ==TZ cra NW - if test xemats differ significamIttly f= .Iz- they inlicalm that mr- ctmmi@l- bm o==rad and fartber research is rG*drmL - such - m am oucrwrtly smailaWs (Aimms, cumtogalicitY, etc.) wiU be used to scrum raw additivea; or 9iWdficm= proomms; dwips bLuq explored in FM to check purImututim fvu the r-- - noww4gr' Cn the jn@j. of , r . scientific and sindical evidnnom, I - appears to be ro juvr4ficatim for seekuq xmmu%s of re&zdzq Valums; measured by the cizimintly available bicamamemys, and this win mt be am Cbjs=iVm of onto= rxdmwftl 3. Additive2l; Wid m"mrials Ad%dma Wm w=k arm providmis a wavim to coamni@ by reviftrim informiatim co p=powd im; =.: Wid mistecials wd =ddTq rm=mmmkt1xm rwpzdiM their CY, C: a- -@4 U4 B.A.T INDUSTRIES P.Lc. MINNESOTA Do@osrroRy COPY - PRODUCED PURSUANT To I VILD. OF CONSENT JuDamEmT DATED 5/8tN IN STATE OF MIAWEsoTA, ET AL V. PHALJP MORRS, Er A" CASE No. C1.9"ses acceptability. It LI= mii@ an warergm of charges in lalislatian and rr..ifw =lt=ity of additions to sP=J V r. WideLirl0s. It mintains a datahme an addit-:ves em=03out the BAT Grow, P=C8dUr25 used f= the Lssessuam of both row wd emstim mstarials v-Lu cmrirm to be devalagped in cmjm=ian with CAC Effort allcmtian ... 171 1. lyfir SMO)a ZI7VirCMWdZ1 TCbW= SjMka 0011tinUm to be a mj= 4cma In the w3ority of the Crays =mksts. with so= rawlatory aumcrities mmestim that oposure to =S my be harmful to mo-smokers and rwxumwdirg restriction on %tA- =ddrg MY oCCUr- M* r6WWCb t@= irk SardIampton hm Im,4 It up a consid-nable dabftm an levels of =S in real World enviromatz and bwft P*gi@@ these rum,21ts widely- FbllowiM the mW mwtiM jn Noymbw Iggg, tha leval of researcft m E33 was ra&=md, bit it is i1qortam that we =Imto= cccqntwm in t2= m@m. The L"l PrOgmm will O=U= to focus an pwviduq f=23=9311. 2r1fCM31MtiQn on the r+@i@l wd phyr.JC&l r&tUrg of ECS, on P-Scral eqmwm debminrcLons through nicatim matabo3 4"!-, and an xubjective aspects of MS. 2. Altba3gh Xwb=d Prcdoctu my over 211123atim qppoirumitim as an J=--tiVS PCO&JIM, tta =St likely driviM foram for inmuhzdm inch pro&=m will. be ffw2x==n61 coca=. FAmmexch to fttm bw indicated that camin CaNtructimm Of CiPrIlfts Papor load to low sidwitzen mirm but m yft we bills no tm32mwgaj the mKbwAm undiwlyiM thU ;bmwmo=, of it is p I that thU is xbxtW in the 1991 , g - in r 4 tb&t r=tbAw qVcmtLmdt1m can be crestmL Addlti=mLlly, gem pr@ - vin be devoted to mplamt:=y z,I I fw low sidmatrmll F=*=tm in SW- b8VAWn PZCfg. 3. As a zmadt of the mmxkatiM Directogoge 2:14 row yrodect has bwa initiated, the primy aid of-h4rh: redL= the wffirctswea, inch's asm=datmd wift cigamme b=ts. 7he PLujact I I El will facm prircipally cm the wyvipi,,tjon of callzilaw am:atzta filt-mm to POZxft Vallim clagraft of depmdWbility mm dimpardwL mile vin be dcm in clam canguitatim With SUCF- OMMidAMtjoin W.LU be qjVgn to th& awb@rA&U =k1M up the ti;puq pWw, the qjum, pbq wag and plaxticism, as wall as to the riymms, A cb@Ckllgt Of the iSFURS rai=d for Inrlimicn in thix rogboNgal , prapmw by the Markatirg njrwcb=, amd TM mmirxp in AUW=t w3d 5 I I TO5PWCtivft1Y, is dwdn in Aamulix 1. IN, B.A.T INDUSTRIES P.L-C. MINNESOTA DEPOSITORY COPY PRODUCED PURSUANT To W.D. OF CONSENT JUDGMENT DATED S18/98 IN. V- PHILIP MORRIS, ET AL. CASE No. C1-94-mS Me work progrm= is based m a Wcal eUcrt of 58 mmv-1mrs in the Fmzk=mtal Ressuch Cw=m wd Win CCSt M.M mill4rU c=pwima With im mist I i i= ao=zlt that the crwtim of the nC t=k affect = Apml and the &Uy mnalized rate far the rAw cw=m for that ywr %vAd hm bm 0.632 millicyl ( g I with the C&C =ffpwAm). cb this besis the in=um iwludlrq irdlatim is 7%. it bas I a =notice over r ymrs to div:kk the Luc=tim of io@@ to the triftmaral resmzrh y=g@ by the ChC =qmnlas a==diM to the faUadrq pazcarmagm: WCo. 32%; SW 30%; BKTCF IR; nL 19%. an thix buis, indi@@ aUccatiom mild b.: BAMOD. C1.2430n. D&W C1.166WU EX= V0.738mn. MM fO.738mn. OA,= separaWy, than is a bxkjatary ru*dranom of fZ96,0DO f=- cdm=al =n=mcts cn mo)dM w3d health (Sciwtific FAsearch GrOW proje= margrjad by Dr. R.E. Tb=ntcn m behalf of the chc caquides). =a cmVerable f*m fcw 1990 in c", 000. Tzaditior^Uy, VLis Jz furded an e9ml sbarm bmis by the fcur om=dbAiM CRC ompwdm, ard tbus f= L"i ccr:=ib=i= wcx,'A be C74,ooo. AWsmont is SW= ft= thb TW to the hdpt of 0-885 3dllim for tha farA*ugfdml 2: .1 progiiam, and i2%,000 fcw SdW=iliC FASIMIrCh QMUP Fmiects. in - of 41=atim fmmula, mw is awwd to agme amw the bist=:ic bmw fcw thms tm bx5ami; cr to cmuigkw an altzmative fadim t--4- which my eiim s= of the tm prahliiiiiii; asmodated vith the auxs= systm A prupoml fcw a ftrdim f-l's wbich softly renects tucwwc of the c=m=lbztiM ompmiy is iLbastrated in Appwdix n. ALA= 22Xt X0vud2W, IM I\:. C_- N cr- -n BAT lmousTRiEs P.LC. MINNESOTA DEPOSMORy Copy PRODUCED PURSUANT To I VILD. OF CONSENT JUDGMENT DATED S/M IN STATE OF MINNESOTA, ET AL V. PHILIP MORRIS, ET AL, CASE No. CI-944W5 Agtion QS& List = 5AXISPS'12 W21=0 and TSRT Ygetj= Mum were a mmber If =am raised at th-W two 111198tinP when wv= to be assured at the mewtiM Of the PAS88rCk' Dire=mrs in 0=- im, far inchmicn, if spprcpri@, in the bmd=W=l research PL=Fmm. me fo] I oi ng ctAcklist sbow the dscisi= of that =Wtim. buis xi--, at mine 232a= 3M1Q0-QZ=XI%r-L =,adsd ttat this PricwitY is wn cmmxud in the c'mosenscry wcdc area. significant of the Materials SciOrcs and Spgc@ai Analytical ucmk armaIi; risk L this =**@a- AU jam=stim In VI= wsl Br@ on the effectx of PhYsicR1 to*= P=Pertim en moidiv qmlity, tc7ftw vith vil- on uftt b-ther Infamistion is needed, win be $-It to Fir- radL= bitterns ard irritISIOn 2. 2i tbo be son in the total @t -bantm m- and wirritaticW are y coyered in the 0101=01111-mY wcwk Arm. 3. Amciated --k M3jA is now inmbxW in the Cbmcam-w: wcmk Prc;cmm'F-' 4. f@r bl!ij@ I-tmlmtw This Is not sow as a pmvject armia for F zdomwdal Pimmiumb- INN will defAm ttw =q- of and ImAMEM t is ptvjo=. aftw dism-im vith otber = 0=pwLt". 5. +m=n4 -4-me ratio Z)js pd=:Lty is covered in the jmwvmt:L!.,e pzo&=tx ams. 6. AU29093ldWe WIM A jmw pLmj@= bw been iwlu&d in tba fxdmmftl a to V=mus this priccit7- mu wcdc will be dome in 7. Z=WM-BZ= am being V.-4 in bom Psc wd Do. mm ccW""jPtjjw'..jjh no Lluplicutdoo Of lit v at varicus- AMA= A =,q,,Vmjr rwAm of cdstiM Jrd=wticn, umb of -'h4r% is by April 2991 c: bamed on c=3*=tmd in will be mm& r@- kV scum C==. cr c_- AM= 16tt, ymmdmr, L090 .4 B.A.T INDUSTRIES P.LC. - MINNESOTA DEPOSITORY Copy - PRODUcED PURSUANT To I VILD. OF CONSENr JuoGuENT DATED 518/98 IN SrATE OF Afwwsom, ET AL. v. PwLP Afoggm ET AL- CASE No. C1 -94-ONS AatP--mtive1=diw Formla Mm ==cm pm=?=W split of a1lo=tixrz by the CXC ampendw is based cin a proposal -1-= the W W-azd2nator in 1986 %hid, was nodined by the MW to rzfL@= s=* of company and its cmY=1bAicn to Q=ip AD and tacbmlogy. 7be I=* of a zathemastiml f-11A %= -Wch amuzibutim con ba @K23mined bas bom a scu=w of cmx:em,- O=rwziy W= is urdw ftm t= auth=itim to aozamt f= its omftib=icne to = and firils the &bow= of a f-'Ato be a rml wmaknem. 3= bffft 4-j 1j- coxm=. In viw of three problimas a fm=,1 a is I that identifim tw almicents: 1. ilixmL= by all ==ibUt= xvne=dn; 'club ammobombip', La. the benefit of having the FIRC facility. 2. a yarimble =St --Vne=irjg the ectent to %*,4cb an individual cmqmw Vill bgnaf4t fr= the reseexch i.e. a t%mmover related &I---nt Tbe simplest way tO c=b2m tam almosts is to =km hLlf of the total qf4xmd1 are the rwiainUr 'variable'. 7be f-21A racummended m basis is: CL - R (0.5 x -Pi + N 'Where C1 in1iVidUL1 ibzt4-n N rn-",-,-W@ of Ccrft-jbUt= Ti net tmmmw of caTtributor In prwA= yww (Ls) = t=1 net ttmovem of cantdbitlas In prwd= yuw (Es) R cost cf al.1 owitmlimad Pja (La. PFC & SFC) (m) in =acticm, to neat two saftwity raWAirmemmes, the cm%zibittans wowit ymbably bays to be rucalaxIated ct year wd wd ammacticm madis such H tmmwvw i-- to& adsting ywc is used. Mm ompwism of c=tmWmticm fcw L990 by cozfties using the cdxtirq and the new *-', Is as follms: bdztirq nc MG Total cm 000 000 cm Ex=. 1.2m 0.096 1.248 241 saw 1.m 0.086 1.173 3-20 N= 0. 690 0.086 0.776 0.704 0. 690 0. 096 0.776 0.738 3.631 0.3" 1 3.973 3.m Zf the famula were spod, the mly issues to be ommidezed such yaw are the amsts of the PAsearcb mWmimmams (boM irAmcnal and mamwxa). B.A.T INDUSTRIES P.Lc. MINNESOTA DEPOSITORY COPY PRODUCED PURSUANT To WI.D. OF CONSENT JUDGMENT DATED 5/&SO IN STATE OF AoRNNESoT4 ET AL V- PHILIP MORM ET ALD CASE No. C1.94-asss L @6-r L-((,@ - Dim= Stratew Fgyiew Mm Hasetim 3= November, 1990 Proposed M -- d, In November 1989 a new structize fcr R&D In the GmW was preposed, the basic of wb'e+% was; that Fundamental FAsearch sballd be , -, - I On am establishment (FRC In Saudompton) and that Other Group RO , 1 1 r 1 1 should cmmentrate cn appl 'ad PAD. An cutlim PW programme fcr the new oantre was presented to the TM with a proposed budget. Since 2st April, utwn tin changes WMV effected, I I have bow a 1. , of meetings with R&D and II I eting Directcrx, an afarme of whiell is the revised PL%grmm now proposed to the MW, in summary fcm. (A detailed research poogramme: has bow distributed to the Cac Rf.D Direct=s for final appLvval). In the program presented a year &W, considerable eapbasis -.ms placed an regulatcry-driven praj -1- (responding either to current or anticipated presz;ares), and an innovative concepts. As a result of the var3x= meetings that base taken place this year this emptmis has signdlumitly changed. Mm need to hrve lbroducts %ftich we mVerior to coepetition (p@xly Milip Iftlarris) is the clear G=;P Priority, and this is now refLected, Ilin the Proposed Flandamwital, FAsearch prIogramna. Mils vack will utftpin the oonsiderable, effort baiM devotad to this challenge by the am' 'ad Ro , 1, . 7be other major change is in the area of Proft--t Irrovation: since the Ormp rocognIzes as first pr2crity the work aimed at strericrity of adating xty3w of pro&=t, the priority an research for nir4- xoz)mtr. has bun in isporbance- Finally, any projects .4--q at radically diaerent cigarettes (c.f. Premier) hm bem largely sholved. Fbr cmTeenieras the Wm* areas covered by the programme are shown in ftm categorim which relate to hrmd bmuiess objectives: 1. D=Wsed cacpstit-tvity through ano)a qzlity 1qorm=wYt. 2. D=vasdd compstitivity tbrcugh Innovative prodticts. 3. Enablingthe Compary to perfcm its. ban@= mndmr increasingly restrictive Regulatory pressures. 4. M-hl4rq th- CmpwW to pwfcm its basines;& under increasim Dwircrawital, concerns. in Practice, there are very few pro3ects that 0WAx%hzte to cinly cra of them busirms cbjectives, but Qhere a single classification wa" be misleading, the paint, is made. 7he proposed star== for the Furdamuftal. PAsearch amtre is r1Q now cutlined with projects gxo4xd under them four clojectives: C', C:) ro B.A.T INDUSTRIES P.L.C. - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To I Vit-0- OF COMENTJuDGmENTDATEDS/SMINSTATE' FAfitMSOTAETAL-V.PtOLIPMORRZ.E'TALCAsENO.Cl-94-MS TEXT MISSING B.A.T INDUSTRIES P.LC. - MINNESOTA DEPOSITORY Copy - PRODUCED PURSUANT To VILD. OF CONSENT JuDo#AEwr DATED 5*98 IN STATE OF MIAMsom Er AL. v. P#@LiP Mogge, ET A" CASE No. C14M-M5 ago 04ality lwrmwo7t Effort allocation 35% i. gxn2xw_A2m FAsearrh mis Aria of research is concerrmd with the relaturshiP of wrilm dmmistry to taste, -11 ard other Or9w1oleptic sensatAons. 7here are two brand objectives: (i) to relate rt-ical and "ical. properties of smo)m (acxmm the full delivery rww) to mokin; sersations as a basis for the devalopmear, of - Jor Pro&xft. (ii) for low tar/nic ratio prodicts, to identify wd overormn the existuv barriers to xwwory PxcJects acizved ommar impact and irritation, -ke- aftertmotA and the sensations of mbody* and Omftftll"o they will relate them Il to ban mddTq behancur. In order to )mW this work rmlevant, =xh of it win be =tWrtWm On satples selected and mVpUmd by Chc coupani". IL T=mr14==rYw"aa===== Z='It'"dt W to give w*p=t to the above projects as a first priority unless an urgent regulatory issm arises. 2. Beluerm 91 Cimmetbe DISIM On &dW 001-ity As a gwmma observation Phillp M=ris t4bacco hi,!h profticas cigarettes of good at - 1,,xw prommIre drill then IRT. 2his is row b&Uaml__tA be JM =@W!r=_Ert_y lnm cbj key featurm affect active or- 316 7 the SR tYMWfttigate_ the =ship batmm ph3mical prqmrties of the tobtm= rod and moking 9mlity. Research win U=b4e the effect of particle density, size ard shape and other ; P, cbwxps on f kw rates ard A CPS. Sin= BA= ard BW Mm gathered 3 t@Z in this ganeral arva, this win bee rwdand before the --,t I - g is defined. OVW I years Soudwipton = has purund a research project, the purpose of wbich bw been to find tobacco treatmtm that rodx* the xubmapent tomstion of minor cmWomes of Interest to Fayulators. As a remit of the various Grmp diammions, this project bas now broaderied wxb that cpportudtims will also be sow;ht, thrush similar meatments, to mvinise the foontien of coq=rds shich lqzom the subjective qwLUty of m-m- Ws Project Arva tt- remuft to both &=)a Qmlity and INgulatory objectives. C:) 0% (JAI B.A'.T JNDuSTRIES P.LC. - MINNESOTA DEpOSITORY COPY - PRODucED pUftSUAW To V11.D_ OF CONSENT JUDGMENT I)ATED 518/W IN STATE OF AIINNESOrA, ET Al_ V. P#v1.1P MORRIS, ET AL. CASE NO- CI'944MS Dmiples of projects to be pmsued ir-13-1a: (i) Generation of navour pLv=== such as =Lim acids, --da and siger by bico-dbemical processes. (ii) 7he affect of xe==tit&-icn processes an quality- (iii) Mu effort of cheadcal and bio-chemical Promases an the formation of minor smoin I (other nmae). (1v) The use of activated cambm or molecilar zieft materials to red" minor Ocnaptitudeft Of -908 or enhance -I- quality. Imlewative EMQ= Effort allocation ....201 As a general Principle g with the ChC oaWanies, any work in this area k1l be aimed at desagning building blocks and not pt.totype products. Ml* setin project in this catepory remains: project fimd= which has, as its objective products giving highly maiified -,- = twrza of composition and delivery. 7b& main thrust of the research ;' 4 is to create 1w tar/hic. ratio I for ublet them is both Marketing and Awgulatairy su;Vcwt- Ibilst a consumer pzoluct trial an the first spin-off of this work in curruttly being M&rW= by MM., with enccuraglM results, the fundstmntal zessarch aimed at reducing the tar/nic. ratio further will include use of cast&-shest materials, cbmdcal I i oil - P of tobacco and Al farm= r4AIM. in the more general -w of creating building blocks, cm of the Is the efficient use of tobacco In obtaining iii's-rogtdred wdratzem and &idestrem deliveries. in cu:crent is an excess of tcbom= In relation to I and thus meeins of creating MZM=U= waicht j are bear PMWAICL Although all wcxk aimed at producing a radical altatmative product that does Wt daipand en tcba= cadmxtim (c.f. Premier) has bsm abandoned, Our am I . generated an Interesting new direcLim based an slution of volatile materialis. (The ta= alu:tim B to the I F, to a streall of volatile materials that are subisequently 414md in coWer regions.) M:ds work has shown that the release of nicatins, menthol and sevexal other flavowmrits to the swd- can be influencied by the nabire of the binding material. His work win =&-inue, and be ' I 1, to include studies, en the migration of ccupoundis within the tobacco rod, and at the specific request of the CRC cmpwdA=, will Are materials migrating ftm packaging materials, since these mg I a source of off-taste problem. CY" B.A.T INDUSTRIES P.LC. - MINNESOTA ClEposrroFty COPY - PRODUCED PURSUANT To VILD. OF CONSENT JUDGMENT DATED 5W98 IN STATE OF AONNESOTA, ET AL AL-, CASE No. CI-944MS alagatory isgas Effort alloation ... zat 1. Rkhxed Ignition B2=W Although at thas stage Only MA has roodations that rAORSSitiktO establishing an nooepted mirthod for cigarette ignition potential, this is expiected to spre-l' to other =mines. CMMM hwm met up a t&* F in %birth BAT has Wan a principal lead. Activities planned for 1991 are: - further collaborative studim Aimed at refinirxj the existing test -thod - fabric evaluations to ensure consistAncy wd UMUOMMity of coatim. In addition to this work wh4e!h is largely conmitrated on din= methods of measuremwit, there will ultlaetely be a i@far IUU= measurements that enable predictions to ha unda nf iemit-Am nntantiwl of ciggargtteg. Ulcrk in this ATW Win ComIence in 1991. 2. Search for Ricassays Them has been considerable renew of our aim In the of Biolo#czLl Testing, antt it is I j I that the following POUCY now UnIMPIM the future research activities in this area: - WX will ncnitor tr-xk In the amoxgurme of nm bioassrys and will drielop expertise in those utlet say have ralwamoe to taboooo products. - Despite t1- uncertainty associated with cu=o= in vi@ I la IN aw their applicability to OCIM34M mixtures, these I la axe ussful in cm way - if test results differ xigrdficantly fram currwit norms t2W iWicate that ame dmical change has c=z=ed wd ftztbw research is reguind. - - S=b I a, as are currently available (Anns, Mastogenicity, etc.) will be used to acreen new additivias or siWdfizant I , - --x.,es being eqaored in RAD to I I parbmtstim frm the rk-- - Hoavver, an the basis of ;z- P"11 scientific and y,ftlieml eVidwm, there gppWrZ to be no justificatim for seekirq means of .-- values -by the currently available bioamiyi, and thJx will not be an objective of current ftd=wAzl rommth. 3. Mm work arm ;rovuies a sernae to cperatuil coqxudes by renomq inf=wtun an pztponed now additives and Uffberiffik's and zekirg rations regazdirg their 01 Ln B.A.T INDUSTRIES P.LC. - MINNESOTA DEPOSITORY COPY - PRODUCED puRsuANT To I VILD. OF CONSENT JUDGMENT DATED 518M IN STATE OF MWESOTA, ET AL v. PH&ip AWRW. ET A-L CASE No. CI-94-MS accaptabi.lity. It also mintains an awareness of cbarxps in legislation and ravieds conformity of additims to Rmcific mick-lines. It noint&ins a database an additives ummugimt the Bu Qmup. PL=o&mw used for the assecownt of both now and anstirg mterials Vill cmtirm to be developed in option with CAC ccopmlies. Md=MWW mmm Effort allg=icn ... 17% 1. Alk V, Dwirunwrital 7bbbooo Swice =*Anm to be a mjw Ismse In the unjority of the Grove. mricuts, Vith soem regulatory mAborities suggesting that eqxmm to Ms may be h*r-,n2l to non-smokerm and iding rowtidmien an iftra mokuq my omour Tba rAw Wilt up a =miserable datmb@ on loyale of MS in real world mWiramuft and hum =mb3 izhmd three row.11tr. widaly. ftllWirq the TSHT Metiri@ in Now@ 1989, the loyal of research on ZIS was rw%xxd, bit it is INPortant that we mintain cmqxtwm in this area. The 1991 progrmw will continum to F -- an providing furidameftal inforgertiM on the e+-i@l and phygiCLI natLIM Of =9, an permal eqx-= doterminaticra throLigh nimtim I II 'it-, and an wAbjective aspects of zm. 2. Total Sidestralm Had=tion Al"-Zb ze&cod aidestxam pro*=tz =W off= umdcating, qV=twdti6s 02 On inmwstivs Pro&=, the M&t likely drivuq form for introd=irv such products Vill be awirmamitai cmumm. FAmomrcb to daft box indicator' that omrb&in of danotte paper land to low sidextrum we ham no txxlmwftl q 2 Of tto =gone,= =YZ this V L. rt is I that this is mbrHad In the l."I I 9 In I that fmrther qWortidties can be cructed. Additionally, mcm effort win be devoted to mplormtory remazcb . for lcw sidestra= j r I I in which effectively the cigerume does not b= bobam pzffs. 3. As a rowlt of the Mrketia.; Directorm I muting, a =w project has bow initiated, the primry aim of %Mirb is to re&= the onvir-umatal problems associated with cigarette kx&U. Mu pwaJor= dwrefdre will focue prir=ip&Uy an the modif=tion of colls'lope acetMm filters to pexuit varying I g of debility dim7mrded. m3da Wm be dam in Clow cmw1tation with WMT. Ozoukrotian will to given to the leterials =Odrq W the tippiTq paper, the gl-, p1%q wrap and plasticiser, as Well as to the f3bres. A cbeddist of the Issues raim-A far J=IuLicn in this fUn*mwgtml M.) reomrch propmme by the mcketinig Direct=, and TW metings in CD M.) Au;k-t and September respectively, is sbmm In AMmidix 1. CT, B.A.T INDUSTRIES P.LC. - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To I VILD. OF CONSENT JuDGmENT DATED SIMS IN STATE OF MINNESOTA, ET AL V. PHILP MORRIS, ET AL, CASE No. CI-9"565 The work yropwm is based on a toml eacwt of sa zww-ysem in the hxdmoftl Research amatre and win cost MM miLlion. ompWisons with MO =at twa irft micommit that the creation of the nc took effect In Aprn and the fully wwouLtsed - f= the ym ml 1 9, for that year would have basm C3.632 xMion (agrod with the CZC CMPWdW). On ULLS NWJA the incrumm ininludiM Inflation is 7%. Xt has bm a practice ever ym= to divide the ,"location of contributicra to the rardisawgal research I 9 by the ChC cmpwdm a==dirq to the follaAng I I I gas: MM. 32%; 1W 30%; MM 194; M 19%. on this besis, irdbt2ml anocations would be- BAW00. C1.243nn. SW M166M. BA= E0.73emn. 17L 0.738m. Quite snarately, is a bj*ptmry ru*dxwwnt of 0%,000 Z= external contracts on immoking a-id bmith (Scientific Ammarch M-p project =ranged by Dr. R.F- Thornton en baboaf of the CRC cmqmi-) - MM colvarlablift flomm for im in 044,000. TraditionAlly, this is f=W on equal dmtw basis bV the faw c2ftibitim CRC comenfes, and ftn for 299i i--b itione would be C74,ooo. haremm*. is foxght ftm the TSU to the bdvat of MM million fw the fundimmental research ptagraimmet, wd =%,ow for - -ant4rin. Ressurch Grow Projects. Zn 'I,,- of allocation forimul&, MW is selmd to agm either the histwic bases fgkr II I tm IxIdgets or to mmidkw an altamativa f0dim basis %beef% my samet somet of the tax ptrblems ammodfilt-& with the aMXU* System. A pmposal fW a ftmdirq formula this% PWtlY reflects VmmWW of that ftutin; cmtmw is illustrated in Aamxxix xr. 229t YoVmdW, MO C) rQ C, I= C7, CD B.A.T INDUSTRIES P.LC. MINNESOTA DEPOSITORY Copy pRooucEv PURSUANT To VII.D. OF CONSENT JuDOMENT DATED SAM IN STATE OF MINNESOTA, ET AL V- PHLF AIORRM, ET AL, CASE No. CI-944US an QWk Llst f= VAd=JW DirliCtims' and TM MWt 7here were a muber of acticm raised at then two meatirgs what were to be considered at the metiril of the Passarch Directors in Octobw 1990, for iwausim, if qpWriate, in the ftdammital research 1 2be fallowing checklist shows the docisicro of that wwtirg- 1. Projects almd at JmdC33&W3JJm the 1 us Lcoim uraducts utdch cmin-em C;O-id- x--icr Z2-fi=M= It was eooClIjdgd that this priority is well covered In the Cbmummunmory work aren. Significant Parts Of the Material% Sciffam and Speditl ArIalytical work arms also address this BU12jeCt. jLU relevant kommatum in WZ7 and SW on the effects of phym@ tobacco properties an amckin; quality, together with viam; an what rmrthw infazimstam is needed, will be sent to FW- 2. Chemosensory research to rG&JOe W==0= and Imitatim With the proviso that bitte=mma should be sem in the total cmitiert of "aftertaste" and that "harshnam" and mi:critaticn" are closely Jimimd, this priority is covered in the Cbmasiumory work area. 3. ASSOCiatad W=k ZQ UMIlerstand Wp)=S' kAbMd9IX M31s JA row inclixied in the chanomensory wcck 1 9 4. DFMICMENt of ium - - , -. WIDLUS=W We is not mom as a project area for Fundmmital Research. BW vill defins the scope of and implement this project, after discussion with othw chc cmvmi-. S. Develop aimu=m Id= We priority is covered in the Drovative Pzc&=tx arm. e Filter A new pMect bas bow Irchrud in the farxWmItal zemrcb me to p-- this primity. 7be wc& will be done in .o-4-/CO3l&borat1m with BLU7. 7. ru of this pricrity, am being pummud In both PW ani BW. 7he tk; a;p=mdus ---,id be complementary with no duplicatim of effort. S. To investigate tcbtm= leaf ammira for AMMUSIM A COMPreba-sive review of adsting inforia2tim, nxh of stdch is r) based an experiments catzIucted in-ft=il, win be mde by April 1991 by sm= Cruz. A1WW C) im Novacher, 1990 C:) OD B,A.T INDUSTRIES P.LC. MINNESOTA DE, .pOSITORy Copy PRODUCED PURSUANT TO VILD. OF CONSENT JUDGMENT DATED SON IN STATE OF MINNESOTA, ET AL. V. PHILP MORRIS, ET AL, CASE NO. C14K-MS Amadix ri Altemitive Rmdirn BMWIA Mw current percentage split of allocaticris by the CAC companim in based an a proposal rrcm the Ro ca-c=1untor in M6 which weis =2ified by the TM to reflect sim of cap and its corYcribution to Q=ip R&D and lack of a ustbeimittical fmm,'-% upm whiet, contribution can Urder to weakness. IM have al"I I ar in vjAw of these pttblams a fcm=,',, is proposed that ider*1fies; two elements: a fired Cost by all contributcmu reflectim 'club mobership', i.e. the benefit of brnM the FW famility. 2. I 33gJ&M2 cost reflecting the extent to which an irAividual caqwq will benefit from the research i.e. a tmumw related element. mbe siWiest way to camoine theme elements is to mke half of the total tried' and the remaindAr 'variable'. The f-y1A recommarxW on this basis is: Ci - R (0.5 x Ti + W) wbare Ci - imuVidual Conbribution (co) N - ' of ountribut= Tj - rorp- +ITV,mer of contributor in pmwjiom yew Cgs) =L - total not Ummmer Of Contrib*JWN in ptvviax yaw (ft) R - cost of all centralimed PAD (i.e. FSC & SIG) (0) mm pract-ice, to I tax INIUMICity r8olirIMMIntil, the CWteAbU!U=W VOIdd probably br4e to be rumloulated at year wid wid correction =aft vxb that tLursomw in the exiI;ting year is tuaL Min competrizon of Contributions for 1990 by cuunf:ries usiM the existing method and the raw fc=,'A is as follow: EICLstim Now PW SIG Tcltla mm LOW am 000 Nam. 1.162 0.086 1.240 2-241 BW 1.009 0.086 1.175 1.289 at= 0.690 0.086 0.776 0.704 0.690 0. 086 0.776 0.738 F 3.631 0.3" 3.M 3.rn C:) 31 the ftnzzla were agrad, the only J sons to be considered r%j each yaw are the , , - of the PAsearch Programmes (both Cy% interml Wd orternal). C:0 B.A.T INDUSTRIES P.I-C. - MINNESOTA DEPOSITORY COPY - PRODUCED PURSUANT To VII.D. OF CONSENT JUDGMENT DATED W8518 IN STA TE OF UNNESOTA, ET AL V- PNX'P MORRIS. Er d6 CASE No. CI-94-MS