S U
P.J.. Rick sq.
a
WEST-MINS SE 7 M:LLSANK LC)NDON "A'.? 'JE' C. 222
12 2 2
!3 t'-- Decez:]:er, 1972
PRIVATE & CONFIDMIAL
TO ALL NO. is OF ASSOCIATE:: COMPANIZ-S
"SMOK-MG AND HEA7TH
S-;mce our last c4zcul=--- there have been rwo
develoDments
of con;iderable inter;st:-
1. Results of exDerimentS carried our at the
Research
institute of the German Cizaretre 1:--dustr.7.
On 21st November the Director of tl-.e lasti--,ze,
Professor Dr. W. Donten-dill, released the results
0 ~
raese e=eriments to the Ger=am zress a--d a
copy of a traaslatiom of the p tress release is
enclosed. As will be noted, it covers twc large
scale series of exner-4-ents or. arim.-C_s; one,
paiati-g
-4 ce w:_th condensate, zhe oraer se=;-E;
ha:_-zters
co inhale whole sm-oke. -c,.,-aes some
It also pr 7
add't-'onal co=ents on Dr. H.P. Hazke's
ex-neriment
in '.he field of passiva smoking, whica was zae
subJecr of our previous circular of 7~;h November.
The full results of r*--a r-do a.-_i=aL
experi=a=-'s have
noz yct been pub!"sined in scJen:-'_"c journ-a-s
and
co::sequently no co=er--, o~ or poSEible
crizicism of thex is 7e-: available. Ln. our view,
however, the f'.'=r_=gs waich are of impozzan-ce
are:-
(a) T--e gas/vapour ::.'-.ase is s-*-o-dn be
inactive
in both experizlenzs.
The inhalation experiment zoduced no tumou--s
in the lungs of zhe hams-.e-s (althou;:'a tumouzs
in the la-77r-x were produced).
(c) In both experiments sheet reconstitu:ed by
certain,
but not all, processes was de=onstraz~d as
being less biologically active than natural
tobacco.
BATCo document for Province of BritiSh Columbia 29
October 1999


- 2 -
(d) Filter cisaxerzes were shown to be less
biolog'ca.lly active t~-an plain cigarettes -
with acetate filters producing the least
activit~y. To a large extezt this is
probab--y attributable to an- overa.11 reduction
in the particulate smoke intake.
(e) The addition of sodium ni::-ate, in both
experiments, achieved a si--iificanrt reduction
'r. biologica-I activity.
f) Bota Vr-ole smoke ar-d condensate were showr-
to
be promoters rather than -' ---; -t.-Iators.
(g) No other diseases (e.g. heazt disease) were
produced by the inhallation experiment.
Zn-formation contained in t'--e press release is
now, of course, public knowledge. if No. ls wish
7 o make use of this information -'a rhe 1-ight of
zheir local circumstances, would --~-Iey please
make
clea---, as set out in the second za~agraph of
this
circulax, that the full results c' the two aziimal
experimen-;s have not yet beer, p:,~'::-Isnec In
scientific
journals.
T'- e c o mm- e r c -; a - and 3 c 4 -an z i f z-
z: -z=n I --*,~ a t i o n S
)f these findingO a-re cu=,en-;Iy =Zer cons
ideratf-on
-n Mi7 ibank and No. is w-.1--- be im rouch wit--
,7 -
C.eVeIODMenZS.
2. Suzar cont~-nt of
-- a p:,ozrimme in the "Tomorrow's '11"crld"
series
on B.B.C. telsvision on 16th Nove=ber, r-~e
t'--eo--7
.;as puz foz-ward thaz suEa-- con-.e=-~ ratbez
raen ,:a~
=ay We7 1 be t~ie most "-.&rmfu.l ele=ez:z im
cigaxeztes.
:~; was Doszulated that the lung cancer rates were
'~--:gher i_- B---itain t*-Ia-- in the U.S.A. and-
France,
because British cigarettes are made of flue-c-ared
tobacco with a higher sugar conter.-,; thar. the
air-cu--ed tobacco which is used in substantial
proporzions in French and Ax-erica- oigare:tes.
This theme was further develoDed in the enclosed
a=t.icle in the Sunday Times on l9rh, November.
Thereafter Dr. Fenner, to whom amo-,-st oz.hers
the
a:T-Lcle refers, was L-iterviewed on Radio 4 on
22nd
Novembez. In this interview he ad=itzec that
t*.-le theory was "very ill-substan~:ia-,;ed so
fax".
CD
LN
BATCO document for Province of BritiSh Columbia 29
October 1999


- 3 -
He added that the theory had a long way to go
befo--e it could be accepted and might well be
wrong.
There is reason to believe, however, that t*--e
SLLnda,7 Times may be planning to publish its.own
league tables for cigarettes, one based on tar
and nicotime content and the other on suga:,
content. J-7 is also thought not unlikely -.~--at
it
will recommend to the smokers amcng its readers
to pay attention to the sugar rankings rat'--e-r
than
the tar rankings.
As ZeFards z-.e si,,7nificance of sugar conten-:
in
cigarezzes, the Tobacco Research Council ha-z been
associated -.,-,th research in this area for a
=Limber
of years and in its view the evidence on rtis
part-
iculax :)-.ob-',em is inconclusive.
It is underszood that the Department of P-e--- and
Social Ser-r-ces in the U.K. will, if it receives
encuiries, be stating that "the evidence on suga.7
so ?ar is 4=conclu. ve T.R.C. will be fc! owi-
the saa. !-me but b;-4ng careful to
emD~,:as-4.~z--that
it .:3 not cualified to make medical judg=en-:s.
It
is zeco=ended tiiat 'To. ls should adopt a
stance, if commenz becomes necessary.
G.C. HARGROVE
Encs.
CD
BATCo document for Province of BritiSh Columbia 29
October 1999