0
CL
0
0
-h
0,
0
0
CD
0
%
0
0
Cr
K)
(A
0
0
r4-
0
Cr
CD
CO
CO
r)
rn
r-
0
0
X
-I!
^7
4
~Z
M
UI
0
7 q
0
CO
r)
r)
0
C:
i
1921
AIM AiTHL)ACH EM! !WNUTU
~jAIOKF OIJALITV
ILIPROVEN1 M.
.11sation of positive effgjcE
C)pfln
To improve smoke quality by Use of Cozymic
111calls Io Cidialle. hol-we 1-1011,1V ... 1. )1
Al
tobacco modification, natural tobacco flavour
reactious pro'hicts.
(that underpin Root technology).
Physical Parameters & Srnnj&
IMMUNIENTAT-ION Prob Ygl!ie rmig
Scale
Pos"11.1c adduion lit a 1".10
vessel' plior to 11MI) for enzymic LIM it Lg
reaction to develop.
To establish a model for Study of interaction of
all New approach to smoking (Iiiality Selection of
blend components,
predicting rod pressure drop and parameters that
affect pressure improvement means of controlling
cut length, -2
for relating effects, ifany, on drop and their
effect on smoke width, shape etc; balance of H L M
smoke quality chemistry and taste. rod/fil
ter/vent ilat ion --k
characteristics.
Smoke Transfer Studies
To explore different mechanisms Systematic
experiments to clarify Better control of delivery
of Through Product Research Group
whereby materials (flavourants, mechanisms and
provide data for materials that contribute
strongly in CAC labs, who are seeking eg.
nicotine, menthol) are transferred e.g. BATCF to
create a model to smoke taste and flavour.
controlled puff-by-puff delivery
to smoke. and coaxial cigarettes. characteristics.
Example - M M M
microencapsulated materials
To devise new techniques for Assessing new
proprietary releasing mouth freshner in last
transferring materials to smoke. materials for
microencapsulation puff.
and (heir performance in burning
cigarettes.
Smoker satisfaction at very low Tobaccos
chemically or other Cigarelles willi the
satist"iction of Tobacco treated in 'extra
lar but normal nicotine by novel wise treated to
reduce tar yield, higher tar delivety cigarelles
1,111 process', perhaps cast as sheet by
cigarette design. cast as sheet if necessary;
tobacco at very low tar. any recon. process.
Blended with L/M If Lg
extracts/flavours will be normal grades.
incorporated possibly by
Key 1. = Low
M = Medium
It = Ifigh
*H = Iligh (Defensive)
Lg Long (4-5 years) 11fol) = Probability of
success
M Medium (2-3 years) Value = Worth to HAT
S Short (I year) Time Scale = Time to application


AI M A P P R OA (: " END RE NE' FIT 1 LI Llj j~ A!
[ f ffA j ] Q N rf (_ill -VA !u e I
S hi
ca Le
le
a
c
I
)
o
II
F
ntr
11,1
u
o
1 i I
ll-
lle
ol m
b
d
k C nact
odi
im
lIm /I
ed
pa
a rr
s
c
ct it
m
t a
c( ati
o
n
hi or
ke
d
le t
w
,
it
h
St
a
sc
Cl
ud
mn
u%
Uf
y
io
or
aL
th
ni
y
te
e
a i
An
fiS
in
re
d
ti
fl
a
C
CS
ue
mi
lie
.
n
e
li
cc
nis
tic-
of
o
A
v
n
a
s
rio
mo
us
k
e
M
pr
ore
od'
p
ICI
le
S
asura
ble
smo
king
A
ap
F
pp
p
m
ro
lie
cl
p
d
ge
ri
to
).
ate
l
N
o1
1
mc
11
c
t
o
rea
(cf
tm
. (
e
T
nt
C
S
L
.
J
M
f
.
g
[
a I)
n T
d i o
rr o
it pt
at imi
ion se
c s
ha m
ra o
ct ke
er i
is m
ti pact
cs E
Im
op sta
o
ti b1
ist
mi ish
ur
se
e
i gu
co
rr id
m
ita e
b
ti -Ii
in
on ne
at
/i s
io
m fo
ns
pa r
t
ct de
ha
. ns
t ily M
pr ore
odu p
c 1e
ts asura bic sino kiog A
d dj
en us
sit i
y me
& ni /c
mo on
is 1r
tu o
re l o f c i9 ar ett e N 1
T
th
o
in
p
o
e
rd
c
ro
u
se
e
or
d
nd
c
r t
p
uc
er
ha
ha
or
ts. F
st
r
t
at lo
a
ac
th
ed d
nd
te
e
i ytM
wh
risti
y m
n lo ou
a
c
ay
w t
t
s
d hf
de
of
b
e id
te
s
e
liv
rm
mo
er
i
k
y
ne
e
s
in
T
di
to
pa
o s
ffe
id
ra
y
re
en
m
nth
nt
ti
ete
e
b
fy
r
si
o
t
s t
ze
dy
he
h
s
/
c
at
m
mo
h
g
ok
ut
em
ov
e
h
ic
er
w
fid
al
n
it
i
/p
th
h
n
h
is
r
ysi
e
er
cal
ffect.
Sa
tis
fyi
ng
sin
oke ;
it lo
w de
livery
U
ir
ve
nc
ea
n
e
tn
til
rt
ie
at
ain
nt
io
-
n
g
S
co
ra
pe
m
d
c
b
e
ia
in
sele
l b
atio
ct
1 e
n
io
nd
s
n
,
an
filt
d/
er
or
,
L
M
L
I
M
L
g
A
ph tte
ys m
ic pts
al
a wi
nd 1l
c b
h e
e m
mic ad
al e t
e t)
ff s
ec ep
ts. arate
T
u
d
..
o
np
r
..
u
l
y-
..
d
ea
m
...
r
sa
ou
..
t
nt
t
...
A
a
a
h'
..
ft
nd
ft
s
....
-p
er
the
erta
ynd
..
eg
T
c
st
ro
..
i
as
a
e
m
...
ll
te
us
in
e
..
ve
es
c1
.
...
e
o
ud
..
ffr
f
in
..
jc
g
....
U
...
A
be
ch
re
be
.I
te
c
e
du
s
...
t
or
mi
ci
ou
...
s
re
cal
ng
gh
..
e
la
c
t
t.
..
e
la
he
..
&
d
ss
s
...
r
w
e
e c
..
y
he
s;
o
...
e
re
m
m
..
s
p
ea
po
...
e
os
ns
ne
.
f
s
n
...
ct
ibl
of
ts
...
s
e t
w
.....
ill
o
ll
...
u
e
o
r
o ......
ing .....
ro ......
uct. ........ ..
1
to
w
ch
co
a ...
r
b
hi
e
m
me ..
u
ac
ch
m
p
Ii ..
g
co
r
ic
ou
or ...
h
g
e
al
n
at ..
r
ra
du
c1
ds
e ...
c
de
ce
as
to
th ..
s
s
th
s/
s
e e ..
s
o
e
or
m ..
t
r
u
a
o
ffe ....
eat
spe
nd
dd
ke
ct. ...
m
ci
es
iti
th ..
n
al
ir
on
at ..
s
fi
ab
o ....
,
lte
le
f ..
s .. ...
M ...
I ... ..
M .. . ... ..
M
A (ly s a fti us C o m p ou n d
T
g
C
m
s o
ov
om
at
mo d
e
p
e
k et
rn
o
ria
e er
in
un
ls
qu m
g
d
t
a in
th
s f
o
lit e
e
r
pr
y prin
mig
om
odu
wil c
r
eg
c
l ip
at
t.
be le
io
pa s
n
ck
Eff
me
of
ag
cc
as
i
ts
u
g
re
n
d In
cl
tr
in ve
ass
an
vo sti
i
sfe
lv ga
nfl
r
ed ti
u
ac
i o
en
ro
n n
c
s
th of
es
s t
e h
th
h
ci o
e
e v
&a w c
sp
ar
re h
e
io
tte e
ed
u mi
o
s
pa cal
f
me
ck
ia
age. Im
'O pr
ff-l ov
ai ed
nts sino
'. ke ( Inali ty - free of A
pr
ba
m pp
in
rr
at li
ci
ie
er ca
p
r-
ia ti
les
co
Is on
i
at
. s
de
ed de
nt
p p
if
a en
ie
ck ds
d e
ag o
g
in n
ne
g
w
M
M
M
W
r)
r-
-A
P1
C)
0
0
--I
0
CO
>
009?0
>
4
0
0
CL
0
0
(D
_h
0
0
(D
0
h
0
0
3
Cr
75-
0
0
Cr
CD


AI M A-P E R -O A C H E, N 1 ). 1 ! 1 " N V A I T
M I' LI N IE N T A TI O N Pr O Y d! !!V 71
S m
ca r,
le
T
r
o
e
o
im
n
1 R
p
st
r- eco
rov
itut
11, n
e
ed st
s
t
11 itu
m
o
1 te
ok
ba d
e
c
~
q
co
J To
ua
.
_ ba
li
C cc
ty
t o
fr
-
om
-
C
ar
of
im
he
e
o
p
ck
va
ff
ro
i
-t
v
w
d.
as
in
he
te
g
th
If
.
q
e
s
S
ua
r c
o,
ee
lit
la
i
k
y
in
de
m
fr
is
nt
ea
o
o
if
n
m
f
y
s
re
of
so
of
c
f-c
ur
on
a
c
.
ste
e
I
fr
m
o
pr
m
ov
re
em
co
e
n
n
-c
t in
on
sm
tain
o
in
ke
g
i
c
lis
ig
ali
ar
t
et
y
tes.
'11
m
pr
1 r
od
o
oll
s/
ce
u
m
Ss
b
a
es
e
.
ma
ria
Ch
l
in
ch
e
a
ry
ng
s
i
r
c
n.
f
1
.
S
T
r
o
o
es
f
p
l st
te
e
p re
t
fo
a l
an
e
Sy
va
ad
fo
st
ri
di
rm
e
ou
ti
a
m
s
ve
ti
at
t
s
on
ic
he
u
e
or
rf
etc
x
i
ac
.
pe
es
e
ri
-
a
me
fil
rea
nt
tr
,
s
at
w
to
io
at
c
n
er
la
ri
fy
K
p
n
ro
ow
du
le
ct
dg
s
e
w
b
it
as
h l
e en
ow
ah
SI
li
S
n
t
g
o
ne
be
w
m
de
A
id
pa
pe
pp
en
p
r
Ii
ti
er
me
ca
fi
b
a
ti
ed
as
bi
o
e
lit
n
me
d
y
wil
ch
on
ch
l
an
n
an
d
i
e
g
ep
sm
w
e
en
e
ad
et
d
g
di
c
on
ne
tiv
th
w
e,
e
H
M
el
o
o $
uc
ns
w 41e
ida
ibl
SIS
a
he
r
pe m
th
rs f
me
e or
c
p m
ha
erf at
ni
o ior
sm
rm
R
c
a
ig T
d
a o
ic
re ta
al
t( l S
re
e d id
du
es es
ct
ig 1r
io
n ea
n
. m
in Re
S/ d
S uct
by io
n n
ovel
s
f
To
e
u
b
cti
se
ac
o
.,
c
ns
o
l
ro
in
d
ke
w
d
it
b
h
y
to
lo
ba
w
c
s
co
m
u
d
e
r
C
S
ig
/S
ar
.
ett
e
d
es
ig
n wi
th
l
o
w
to
ta
l
R
all
Se
od
o
ct
c
w
io
o
a
n
ns
l
to
tr
ow
b
uc
-s
e
tio
m
n
ou
l
mo
de
di
r
fi
N
ed
se
to
i
l
M
M
T
p
c E
o
u
o n
g
bl
nt yi
e
ic
ro ro
ne
at
1 l nm
rat
ion
eAl e
e
,
en ni
d
o
v al
at
n
ir T
a,
E
on o
g
TS
m b
e
e ac
ner
pr
nt co
al
od
s. S
ly
uc m
f
e oke
or
d in
p
o
C
m
a
r
he
on
rti
ga
m
it
c
ni
ic
or
u1
c
a
ed
ar
s
l
e
an
ch
as
m
d
a
s
p
n
ng
m
ha
ic
es
o
si
ot
t
ke
s
in
o
ag
on
e.
be
e
v
:
o1
a
il
e
K
ca
in
n
n
it
ow
b
iat
1 e
e u
iv
dg
s
es
e
ed
.
b
i
as
n p
e of
ubl
E
ic
T
a
S
ff
w
ai
hi
rs
c
h
D
th
m
A
is
ro
ee
ff
se
ug
ti
air
m
h
ng
s
in
s
s
D
at
ci
.
e
io
en
Su
pa
n
ti
p
rt
of
fic
po
me
fi
j
rt
n
nd
ou
it
ts.
i
r
)
ng
na
Pu
s
ls,
bli
c
f
1
1
S
S
r
d u
e1
e bj
at
ve ec
io
lo ti
n
p v
t
m e
o
e as
lo
n(. s
w ess
S m
/S e
c nt
ig o
a f
re( ET
te S i n D
im
et at
p
c. a
ro fo
ve r p
d r
F od
T uc
S ts w
odo h
ur ic
, i h
f l
fil cad
an t
c o
y "
D r
ev ou
e1 g
op h fe
me ed
nt ba
. c k to P ro du ct L/ M M M
T
d
o
is
h
in
a
t
ve
eg F
C
rat ilt
A
e i er
fi
n
It
t M
er
he at
s
e er
th
n ial
at
vir s
o
m
e
t.
d
t
To
e
o
r
gr
co
ep
ad
n
l
a
tr
ac
bl
o1
e
e
1 e
pl
gl
d
a
u
w
sti
e
e
ci
an
at
se
d
he
r
ex
rin
w
p
g
ith
os
.
e
il
t
rs
E
pr
nv
o
ir
du
on
ct.
m
e
nt
all
y fr
ie
nd
l
y
Re
se
gl
p
tti
ue
la
ng
.
ce
p
bi
la
o-
st
or
ici
p
se
ho
r
t
w
o d
it
e
h
gr
fas
ad
t
ab
e
/
H
I
H
L
g
T
fi o
lt h
er a
. vv a to ta fl y bi o deg r ad ab 1e T
P o
u i
ra nv
ce e
l1 sti
p g
a at
pe e
r bi
fi o
lte de
rs gr
. ad a bi lit y of E
pr nv
o ir
du on
cf. m e nt all y fr ien d 1y Us
cig e
a o
re f
tt ne
e w
pr p
od ap
u er
cti
o filt
n. er s in Mi 1l *1 1 M
M
__4
r1 l
0
0
-/.
'.Z.
0 G 9 F 0
0
0
CL
0
0
C
3
(D
3
-91
0
<
0
h
00
0
0
Cr


V-![M JO)e
Y
Scale
M *li M
H *11 Lg
M/H *11 S-M
*Ii Lg
JM I-g
L M
LIM
1.
LIM
R
E
G
U
L
A
T
OR A
Y M
I
SS
U
E
S
T
in
i
g
o
n
iv R
d
co
or
e ed
ev
lla
de
n t uc
el
b
r
o l ed
op
or
th
e I
a
at
at
gi g
r
io
g
s1 nit
el
n
ui
ato io
iab
wi
da
rs n
le
th
nc
i Pr
t
C
e
n t ov
est
O
ca
hi e
R
n
s ns
m
E
b
a it
et
S
e
re y
ho
TA
a.
d
E
f
t
e
x
ur
es
.g
ma
p1
ni
ts)
.
te
or
sh
a
he
ria
e
in
n
at
ls
ho
g
dj
tr
)
(h
m
nc
an
tes
d
at
fi
s
t
i
er
~c
fer
m
mA
ial
A (
t
eth
(
s i
m
hr
o
hu
n
ea
ou
ds,
r
m
s
g
nin
oc
uri
h
g
k-
ng
i
p
B
m
d
ill
A
et
ev
ip
T
ho
elo
or
wil
ds
p
tan
l
th
me
c
bt:
at
nt
e
'
a
P
wo
on
re
ar
ul
-t
u
a
d
op
s
m
b
'
ed
et
e
o
-,
er
id
f
p
s
e
te
ro
o
nt
st
du
f
ifi
(
ed. T
c
p hr
iga
fop ou
re
e gh
ttes
nsit Pr
o
y. o
f du
lo ct
w d
ig ev
n el
iti op
on m en t of
T
m
a
o
e
p
k
th
pl
ee
od
y t
p
s
o
ab
th
ci
r
at
ga Bi
ea
l
re ol
st
eg
tt og
of
isl
es. ic
b
at al
iol
or
o
s
gi
m
ca
ay
l
T
b
h
r
o
io
o
el
m
as
us
ev
o
sa
e i
an
ni
y
n
c
to
s.
th
e t
r t
D
os
o
re
e
e
to
nd
ve
th
ba
s
lo
at
cc
in
p
un
o
ne
ex
ig
pr
e
h
o
w
fl
t h
du
se
av
cts
i
e
-
B
n
to
A
e'v
b
T
r
e
is
eg
me
pr
ul
t.
ep
aw
ar
c
ed
y r
i
e
n
(It
th
tk
e
e
e
ni
v
e
ent
nts
that
have
C
s
o
s
c
ur
cre
rde
ign
urr
re
en
r
if
e
nt
ne
to
ica
nt n
me
w
en
nt
or
th
a
su
pe
m
od
dd
re
tu
,
s
it
t
rb
a
iv
ha
at
re
es
t t
io
u
e
h
n
se
tc.
ere
s f
d t
i
a
ro
o
n
re
m
n
o
T
p
m
e
o
ro
e
xt
e
d
et
e
ns
uc
r
rna
ur
t a
eq
l A
e
d
ui
st dd
th
di
re
an it
at
tiv
d
da iv
B
e
in
rd e
A
s a
ter
s. Ma q e_a
a
ri
ni
a
es
ls
'
T
p
(
n
o
e
ch
e
c
rfo
e
ce
he
r
mi
ss
ck
ma
ca
ar
a
n
l
y.
1 l
ce
or
a
o
b
va
f a
iol
ila
dd
og
b1
it
ic
e d
ion
al
a
a
)
ta
l t
wh
;
es
er
s
e
B
re
A
q
T
uir
pr
em
od
e
uc
nts
ts
.
rn
e
et
a
1 l
l
eg
isl
ative
T
hr
Com
mor
ou
p
e
gh
ani
bro
di
es
ad
re
a
1 y
ct
nd
,
iv
o
w
es
ff
he
t
er
re
o
in
n
B
g
ee
AT
ad
de
C
vi
d
o
ce
.
T
nd
n C
al om
ma
an p
te
d
D eli ve ry C o nt ro l
T
s
m o
m
o o
o
d pt
ke
ifi im
co
cat is
m
io e
p
n le
on
. ve
en ls
ts o
b f m
y i
to no
ba r
c
co
f
f
c En
mi
ro
or
ar zy
no
m
fl
b m
r
c
a
on ic
co
el
vo
m tr
m
lul
ur
o ea
po
os
an
no t
n
e
ts
x me
en
, e
o
id nt
ts
ith
r
e. to
ge
er
do m
ne
u
wn o
r
p di
at
w
wa fy
ed
ard
rd
s
s e
g
g C
re
i ig
g
mp Hr
ula
ro ett
to
ve es
ry
Al th
re
sm at
q
o 1u
ui
ki e
re
n et
m
g a
e
qu n
nt
a fi
s
li ci
a
ty l)al
nd/
. m
or As i) hut di ff er e m e nz ym es .
T
u
r
o
se
ed 1
r
d
u 1tr
ed
in
ci a
uc
c
ng Li
e
ig
al g
th
a
l ht
e
ret
sm W
a
te
o ei
mo
s a
ke gh
un
s
d t
t
a
el St
of
m
iv ru
t
ea
er ct
ob
n
ie u
a
s
s. re
cc
of
o
c
u
i Re
o
s
no du
mp
e o
rg ce
o
f
a d
ne
ti
ni e
nt
th
c liv
s
er
fill e
of
f
e rie
M
oa
rs. s
I
me of
S a
d m
nd
io a
b ny
S/
ae
S
co
by
o
r C
a
c ig
nd
on ar
S
ve eii
/S
nti es
y
o w
iel
nal it
ds
d h l
y
in o
et
te w
o
n m
f
si
o ai
ns ns
. ire am
i Foa
or h
nco m
ig
r ed
h i
por re
no
ate co
rg
d n.
an
in e
i
b g
c r
le b
e
n y e
co
ds xt
n.
. ru si on ,
S
c
el
o
e
m
cti
po
ve
ne S
fi
nt el
lt
s. ect
ra iv
tio e
n Fi
o lie
f g rs
as
p
h
a
se
p
'
Ac
h
o
me
tiv
as
ff-t
m
at
els
as
br
e
e
te
an
d
mi
'
e
car
-v
(du
to
b
o1
e
p
on
at
t
ro
c
ile
o S
te
an
s
N
ct
re
bu
's
C.
m
t
)
-
o
ha
fi
ve
s a
Us
lte
g
n
e
r
as
F
co
(a
ilt
m
r/
ers
po
nic
a
ne
ot
bl
n
in
e t
ts
e,
o
re
re
lat
d
i
uc
ve
e
t
o
mi
no
r
S
pe
ci
al d
es
ig
n
o
f f
ilt
er
.
r)
.0
.4
11
r
r)
r)
0 0 9 ZOS
V
03
i
0
0
M
0
0
C
3
(D
0
<
S.
0
0
0
Cr
0
0
0
(D
CO