.31st Ootobere 1966 Dr. A. Roftann, Battelle-InstItut O.Y., Fkw*jurt am Main W13, Wlesbadenerstresse, W. 001many. Dear Dr. Hofmanns In the absence of Dr. Ayres I = earxIIng by Air Parcel Posts- 4 Cambridge FIlter Holders, Complete 2 Spare 000 rings approx 200 Cambridge filter pads. I have also arranged for the withdrsual of approximately 1000 cigarettes Code No. 22400,3 which will be dispatched Vithin the next two days., Yours sincerely# W S.R. Evelyn c.c. JANUS Pile 4 :b. CO BATCo document for Province of British Columbia 5 November 1999 Cop), for: JANUS File DGF/VC/460-2 31 st October, 1966 Dr. R. R. Griffith, P.O. Box 6S9, LOUISVILLE 1, Dear Bob, JMUS - VICEROY SAMPLE The toxicity trial with the Initial sample of 20,000 cigarettes, which you sent us, is now under way. As you know. the main test Is scheduled to start on Ist Jnnuary 1967 and, as we can expect some minor difficulties in sbipping the cigarettes to Battelle over the Christmas holidays, we would prefer to send the first quarterly shipment by the middle of December. it would consequently help us in our planning if you could give me some indication of when we ony expect to receive, at Southampton, the consignment of BZ cigarettes. By the time you receive this the Tobacco Chemists' Conference will be over and Nally and Geoff flook will be at Louisville. I hope you are all enjoying the got together. With kindest regards, C.C. Dr.S.-I.Creen Yours sincerely, ON CD -r-1- co BATCo document for Province of British Columbia 5 November 1999 Copy for: -JANUS, File UGF/VC/40-2 Dr. If. Wedroich, Battelle Institut 1r.V., FRA14KFURT A%' ?M1111 IfJ3, Ifiesbadenerstrasse. Dear Dr. Medrelch, 31 st October, 1966 I o-n writing to confirs my telephone conversation with YOU this rurnini! d1jrJn7 Which wo agreed that the done level for the sectind len '!, terr, test (Test RI - Fffect of puff VVIII,ce) will 1"C fixed nt 50 mp. 11aving %tudied the mortnItty figuyes of tj)e mjc,~ tound during the Inst month. We have COne to Vic save- conclusion as you at Frankfurt that any attevipt to raise the dose level at this time to 7 S A9. nay 3vopardise the whole exi,erlizent h9cmu-se, of the possible further increase in rnrtality. It would seem that the V ml. rulf volune produces condensate which Is twore toxic then mlptht be exrected. Dr. Ayres may rerhats have already discussed this matter with you, but I would be ;trateful if you could ntrsnre for "r. Kiendl to re-check the nicotine contents of the three condensate% produced st different puff volunes. I understand that there is no significant difforence in these cnntents whenjainted Rt the sano level of candonsnte, In which case t s points to an interesting difference In the toxicities which any be due to other components. As requested in your recent hand written notep we are arranging to send yott the re-4brtdpe filter holders and filter pods required for the c1liastasix tests (Tests CAI and CA2). 1% will also send you a further consir.nment of cigarettes, Code 22419931, In P.rder to complete the toxicity tests before the third long term test. We i4 my send you slightly less then the 1000 cigarettes for which you asked because we shall retain a snall. reference sample for checking with the noin batch of cigarettes when they arrive. C, CD -P- C:) BATCo document for Province of British Columbia 5 November 1999 Dr. If. Medreich 31 st October, 1966 I have also started enquiries going as to the wheresibouts of the Pample R973 which should have been despatched fret) Lon-lon Airrort on October 27th. if T have a reply tit time, I will Include it as a postscript. With kindest regards, Yours sincerely, C.c. Dr.W.Schwlck roilowinr cur second telephone conversation today, during which you told vie that the cigarettes were In custo=s at Frank[Lirt, we will take no further action. Not on original or Dr. Schwick's copy: C.c. Sir Charles Ellis Dr.S.J.Green JANUS File 21 C5 U 01 UI BATCo document for Province of British Columbia 5 November 1999