Mrs. M. Ayles
GS/DM/46D
G. Smith
16 th June, 1988
I understand from our discussions that you wish to
evaluate the influence of a number of additives
applied at the
10% level to cigarettes. Each additive is to be
added singly
and it is proposed that in limited panel testing
any one
panelliet will smoke a maximum of 20 cigarettes.
The
additives you listed are as follows:
1. Lactic Acid
Allowed at the 2% level by the ISCSIT (4th
Report). As
your proposed level is 5 x above this value it
would be
prudent to evaluate on intermediate level first in
order
to ensure there is no adverse reaction.
2. Potassium Sorbate
In general use potassium sorbate is applied at
levels of
less than 1%, it is thus unlikely that a 10%
inclusion
could be recommended without more detailed
evaluation
such as smoke chemistry. The ISCSTI allow
potassium
sorbate at O.S%.
3. Promlens Glvcol
Maximum level permitted by the ISCSIT is 6%,
however it
may be included at 10% for limited panel testing.
4. Glvcerol
Allowed by the ISCSH at up to 10% thus may be
evaluated
an described.
The level of inclusion requested in an order of
magnitude greater than generally agreed limits
(exception is
glycerol). I also understand that changes in smoke
chemistry
may include increased formaldehyde delivery and,
in blended
products# hydrogen cyanide. Thus full
consideration should be
given to using an low a levol of additive an
possible to meet
the alms of the project. In addition, due to the
elevated
levels, taking the work further would call for
more detailed
smoke chemistry, plus other supporting evidence to
show that
the modification is acceptable.
455;e
c.c: Dr. R.R. Baker
Dr. D.P. Robinson
G. MaTH
CD
.10
CO
CO
XN.
BATCo document for Province of BritiSh Columbia 28
October 1999