UCSF Journal Club: Research Published by UCSF Scientists
Access articles mentioned in the Synapse column, "UCSF Journal Club," by Alexandra Greer.
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Featured Articles, November 12, 2009
PHARMACOLOGY: Predicting new molecular targets for known drugs. Keiser, M.J.; Setola, V.; Irwin, J.J.; Laggner, C.; Abbas, A.I.; Hufeisen, S.J.; Jensen, N.H.; Kuijer, M.B.; Matos, R.C.; Tran, T.B.; Whaley, R.; Glennon, R.A.; Hert, J.; Thomas, K.L.; Edwards, D.D.; Shoichet, B.K. ; Roth, B.L. Nature. (epub ahead of print) ![]()
NEUROBIOLOGY: Retinoic acid from the meninges regulates cortical neuron generation. Siegenthaler, J.A. ; Ashique, A.M.; Zarbalis, K.; Patterson, K.P.; Hecht, J.H. ; Kane, M.A.; Folias, A.E.; Choe, Y. ; May, S.R.; Kume, T.; Napoli, J.L.; Peterson, A.S.; Pleasure, S.J. Cell. 139(3):597-609. ![]()
November 5, 2009
IMMUNOLOGY: Cytomegalovirus-specific, high-avidity IgG with neutralizing activity in maternal circulation enriched in the fetal bloodstream. Nozawa, N.; Fang-Hoover, J.; Tabata, T.; Maidji, E.; Pereira, L. J Clin Virol. (epub ahead of print)
IMMUNOLOGY: A novel human CD4+ T cell inducer subset with potent immunostimulatory properties. Ndhlovu, L.C.; Leal, F.E.; Eccles-James, I.G.; Jha, A.R.; Lanteri, M.; Norris, P.J.; Barbour, J.D.; Wachter, D.J.; Andersson, J.; Tasken, K.; Torheim, E.A.; Aandahl, E.M.; Kallas, E.G.; Nixon, D.F. Eur J Immunol. (epub ahead of print)
CANCER BIOLOGY: Increasing incidence of neuroblastoma and potentially higher associated mortality of children from nonmetropolitan areas: analysis of the surveillance, epidemiology, and end results database. Hsieh, M.H.; Meng, M.V.; Walsh, T.J.; Matthay, K.K.; Baskin, L.S. J Pediatr Hematol. (epub ahead of print)
MEDICINE: Variability in interpretive performance at screening mammography and radiologists; characteristics associated with accuracy. Elmore, J.G.; Jackson, S.L.; Abrahan, L.; Miglioretti, D.L.; Carney, P.A.; Geller, B.M.; Yankaskas, B.C.; Kerlikowske, K.; Onega, T.; Rosenberg, R.D.; Sickles, E.A.; Buist, D.S. Radiology. (epub ahead of print)
October 29, 2009
IMMUNOLOGY: A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. Hsu, Lih-Yun; Tan, Ying Xim; Xiao, Zheng; Malissen, Marie; Weiss, Arthur. J. Exp. Med. (epub ahead of print) ![]()
MEDICINE: Selective chloride loading is pressor in the stroke-prone spontaneously hypertensive rat despite hydrochlorothiazide-induced natriuresis. Schmidlin, Olga; Tanaka, Masae; Sebastian, Anthony; Morris, R Curtis Jr. J. Hypertension. (epub ahead of print) ![]()
October 22, 2009
VIROLOGY: An enhanced single base extension technique for the analysis of complex viral populations. Webster, D.R.; Hekele, A.G.; Lauring, A.S.; Fischer, K.F.; Li, H.; Andino, R.; DeRisi, J.L.. PLoS One, 4(10):e7453.
CELL BIOLOGY: Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block. Chatelain, F.C.; Gazzarrini, S.; Fujiwara, Y.; Arrigoni, C.; Domigan, C.; Ferrara, G.; Pantoja, C.; Thiel, G.; Moroni, A.; Minor, D.L. PLoS One, 4(10):e7496.
NEUROBIOLOGY: Cortical representation of ipsilateral arm movements in monkey and man. Ganguly, K.; Secundo, L.; Ranade, G.; Orsborn, A.; Chang, E.F.; Dimitrov, D.F.; Wallis, J.D.; Barbaro, N.M.; Knight, R.T.; Carmena, J.M. J Neurosci. 29(41):12948-56.
GENETICS: Giardiavirus internal ribosome entry site has an apparently unique mechanism of initiating translation. Garlapati, S. Wang, C.C. PLoS One. 4(10):e7435.
PSYCHOLOGY: The relationship of multiple aspects of stigma and personal contact with someone hospitalized for mental illness, in a nationally representative sample. Boyd, J.E., Katz, E.P., Link, B.G., Phelan, J.C. Soc Psychiatry Psychiatr Epidemiol. (epub ahead of print)
October 15, 2009
MEDICINE: Effects of Cigarette Smoke Exposure on Clot Dynamics and Fibrin Structure. An Ex Vivo Investigation. Barua, R.S.; Sy, F.; Srikanth, S.; Huang, G.; Javed, U.; Buhari, C.; Margosan, D.; Ambrose, J.A. Arterioscler Thromb Vasc Biol. (epub ahead of print)
CELL BIOLOGY: Axonal/Glial Upregulation of EphB/Ephrin-B Signaling in Mouse Experimental Ocular Hypertension. Fu, C.T., Tran, T., Sretavan, D.W. Invest Ophthalmol Vis Sci. (epub ahead of print)
CANCER: A Novel PTEN-Dependent Link to Ubiquitination Controls FLIPS Stability and TRAIL Sensitivity in Glioblastoma Multiforme. Panner, A.; Crane, C.A.; Weng, C.; Feletti, A.; Parsa, A.T.; Pieper, R.O. Cancer Res. 69(20):7911-6.
EPIDEMIOLOGY: Ventilator-Associated Pneumonia in a Neurologic Intensive Care Unit Does Not Lead to Increased Mortality. Josephson, S.A., Moheet, A.M., Gropper, M.A., Nichols, A.D., Smith, W.S. Neurocrit Care. (epub ahead of print)
October 8, 2009
VIROLOGY: The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapy. Rosenblum, M., Deeks, S. G., van der Laan, M., and Bangsberg, D.R. PLoS One. Sep 29 2009.
GENETICS: Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates. Ripamonti, C.; Orenstein, A.; Kutty, G.; Huang, L.; Schuhegger, R.; Sing, A.; Fantoni, G.; Atzori, C.; Vinton, C.; Huber, C.; Conville, P.S.; Kovacs, J.A. J Infect Dis. Oct 1 2009.
GENETICS: Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility. Johnson, M.K., Clark, T.D., Niama-Meva, D., Rosenthal, P.J., Parikh, S. PLoS One. Sep 30 2009.