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Databases - Cancer Genome Anatomy Project
 
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Cancer: Databases - Cancer Genome Anatomy Project
cDNA xProfiler (Website)
The cDNA xProfiler is a tool that compares gene expression between two pools of libraries. For a gene to be "present" in a library pool, there must be at least one EST sequence found in the UniGene cluster for that gene.
 
The Digital Gene Expression Displayer is a tool that compares gene expression between two pools of libraries. In contrast to the xProfiler, the DGED treats the presence of a gene in a library pool as a matter of degree. It compares the "degree" of presence of a gene in pool A with its "degree" of presence in pool B.
 
FISH-mapped BACs (Website)
CGAP is generating a set of BAC clones (available to the public) that have been mapped cytogenetically by FISH and physically by STSs to the human genome. The BAC data is integrated into various CGAP and NCBI databases to provide related clinical, histopathologic, genetic, and genomic information.
 
Gene Finder (Website)
The Gene Finder tool finds one gene or list of genes, based on selected search criteria. Each "found" gene is linked to a Gene Info page which provides selected gene data and links to various NCBI and NCI databases.
 
The GLS Tool finds all the genes expressed in a single cDNA library or group of cDNA libraries. It then classifies the genes as unique or non-unique, and then further identifies the genes in each of these groups as known or unknown.
 
GO Browser (Website)
The Gene Ontology Browser classifies human and mouse genes by molecular function, biological process, and cellular component. This database is best viewed in Internet Explorer.
 
The Library Finder tool can find a single cDNA or SAGE library or a group of libraries, depending on the search criteria selected. The search first returns a Library List page, from which each library is linked to its own Library Info page. This page contains sequence and clone information and details of the library's preparation.
 
The information in the Mitelman Database of Chromosome Aberrations in Cancer relates chromosomal aberrations to tumor characteristics, based either on individual cases or associations. The Cancer Genome Anatomy Project has developed 5 tools to help with analysis of information in this database.
 
Nucleotide BLAST (Website)
The Basic Local Alignment Search Tool (BLAST) is a set of specialized search programs which find similarities between either protein or nucleotide sequences. Here, CGAP provides an alternative interface to this tool to specifically ask whether a DNA sequence is similar to any UniGene clusters. If a gene similarity is found, a link to the Gene Info page is provided.
 
The recurrent aberrations were derived from the Mitelman Database of Chromosome Aberrations in Cancer (2002) and include all cytogenetic changes present in at least two cases of the same morphologic entity, and, whenever applicable for solid tumors, within the same site. The complete karyotypes, patient characteristics, and references are found in the Mitelman Database of Chromosome Aberrations in Cancer.
 
SNP Gene Viewer (Website)
The Gene Viewer is a graphical display tool. Both CGAP SNPs and SNPs submitted to the NCBI dbSNP database by other investigators are shown in the context of transcripts, open reading frames and protein motifs.
 
SNP500 Cancer (Website)
The goal of the SNP500Cancer project is to resequence 102 reference samples to find known or newly discovered single nucleotide polymorphisms (SNPs) which are of immediate importance to molecular epidemiology studies in cancer. SNP500Cancer provides a central resource for sequence verification of SNPs.
 
 
 
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