The Anti-cancer Agent Mechanism Database is a set of 122 compounds with anti-cancer activity and a reasonably well-known mechanism of action.

This resource contains information on the results of chronic, long-term animal cancer tests. It provides a single, standardized and easily accessible database that includes sufficient information on each experiment to permit investigations into many research areas of carcinogenesis. Both qualitative and quantitative information on positive and negative experiments are reported, including all bioassays from the National Cancer Institute/National Toxicology Program (NCI/NTP) and experimental results from the general literature that meet a set of inclusion criteria.

This database provides carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition data provided by the National Cancer Institute.

The IARC Monographs series publishes authoritative independent assessments by international experts on the carcinogenic risks posed to humans by a variety of agents, mixtures and exposures. Since its inception in 1972, the series has reviewed more than 860 agents, and IARC Monographs have become well-known for their thoroughness, accuracy, and integrity.